Periodontal bacteria influence systemic diseases through the gut microbiota.

Many systemic diseases, including Alzheimer disease (AD), diabetes mellitus (DM) and cardiovascular disease, are associated with microbiota dysbiosis. The oral and intestinal microbiota are directly connected anatomically, and communicate with each other through the oral-gut microbiome axis to establish and maintain host microbial homeostasis. In addition to directly, periodontal bacteria may also be indirectly involved in the regulation of systemic health and disease through the disturbed gut.

Astaxanthin inhibits inflammation of human periodontal ligament cells induced by lipopolysaccharide.

Objectives: Human periodontal ligament cells (hPDLCs) are important source of periodontal tissue reconstruction. Under chronic inflammation, the multi-directional differentiation potential and chemotaxis in hPDLCs are decreased. Therefore, inhibiting inflammatory microenvironment and improving the functional characteristics of stem cells can better promote periodontal tissue reconstruction.

Effectiveness of orthodontic temporary anchorage devices in canine retraction and anchorage preservation during the two-step technique: a systematic review and meta-analysis.

Background: Temporary anchorage devices have been used for decades in orthodontic practice for many applications. The aim of this systematic review was to assess the effectiveness of orthodontic temporary anchorage devices in canine retraction during the two-step technique.

Methods: A search was systematically performed for articles published prior to June 30, 2019 in five electronic databases (PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, Scopus).

Prevalence of malocclusion in Chinese schoolchildren from 1991 to 2018: A systematic review and meta-analysis.

Background: Malocclusion is a common oral health problem in schoolchildren. Literature describing the prevalence of malocclusion varies substantially across China.

Aim: This study identified the epidemiological characteristics of malocclusion among Chinese schoolchildren from 1991 to 2018.

Prevalence of temporomandibular disorders and its clinical signs in Chinese students, 1979-2017: A systematic review and meta-analysis.

Objective: This study intends to assess the prevalence of temporomandibular disorders and its clinical signs in Chinese students.

Materials And Methods: Search strategies were performed in seven electronic databases, and the reference lists from potentially relevant studies were searched manually. Only observational studies that met the eligibility criteria were selected.