Attention-deficit/hyperactivity disorder (ADHD) has been reported exist abnormal topology structure in the brain network. However, these studies often treated the brain as a static monolithic structure, and dynamic characteristics were ignored. Here, we investigated how the dynamic network reconfiguration in ADHD patients differs from that in healthy people.
View Article and Find Full Text PDFBackground: Studies at specific frequencies have shown abnormalities in brain functional networks among mild cognitive impairment (MCI) and Alzheimer's disease (AD) patients. Previous studies have failed to take into account the possibility that optimal cognitive integration requires interactions between different frequency bands.
Purpose: To study whether there is abnormal cross-frequency integration in patients' brains during disease progression.
Objective: Some static network studies have suggested that the community structure in the brains of ADHD patients is altered. However, ADHD is now increasingly regarded as a disorder of neural dynamics, but the dynamic reconstruction of brain communities in ADHD patients is far from being understood.
Method: Forty-two ADHD patients and fifty healthy controls participated in this study.