Prevalence and associated factors for pterygium in a Chinese rural population with type 2 diabetes in a cross-sectional study: Jiangsu Diabetic Eye Disease Study (JDEDS).

Purpose: To investigate the pterygium prevalence and evaluate risk factors of pterygium in rural type 2 diabetic (D2M) patients aged 50 years and above in Funing Country, Jiangsu Province, China.

Methods: A cross-sectional ophthalmic survey was conducted in type 2 diabetes mellitus (D2M) patients aged ≥ 50 years in Funing County, Jiangsu Province, China, which was named Jiangsu Diabetic Eye Disease Study (JDEDS). All participants underwent a comprehensive questionnaire and ocular examination.

[The prevalence of appositional angle closure among adults aged 50 years or above in Funing county Jiangsu Province].

Objective: The purpose of the study is to determine the prevalence of appositional angle closure in persons aged 50 or above in Funing County.

Methods: Cluster sampling randomly selected residents in Funing County aged 50 years or above. From March to May 2010, 484 eyes of 243 patients with the shallow peripheral anterior chamber and the anatomic narrow chamber angle, which was determined by Van Herick technique and gonioscopy, were collected from 5202 individuals.

[Study on gene-gene, gene-environmental interactions of DNA repair genes related with age-related cataract].

Objective: To investigate the interaction between polymorphisms and environment factors in age related cataract (ARC).

Methods: Population-based case-control study. All of 448 cataract cases were selected from cataract eye database and 248 controls were recruited from Funing county.

[Cataract risk factor survey in Funing county of Jiangsu province].

Objective: To investigate the risk factors of cataract among people aged 50 years and above in Funing county of Jiangsu province.

Methods: Case-control study. All of 1 488 cataract cases were selected from cataract patients' database and 1 821 subjects without visual impairment were recruited as controls from Funing county who were examined between June 2010 and May 2011.

[Prevalence and surgical status of cataract among adults aged 50 years or above in rural Jiangsu Province].

Objective: To survey the prevalence, operative status, surgical coverage rate and social burden rate of cataract blindness among older adults aged 50 years or above in 2 typical counties (district) of Jiangsu Province, China in 2010.

Methods: Cluster sampling was used in randomly selected 12 867 individuals aged 50 years or above in 58 clusters in Funing County of Northern Jiangsu and Binhu District of Southern Jiangsu. Among them, 12 053 individuals received visual acuity and eye examinations (response rate 93.

Copy number variations of DNA repair genes and the age-related cataract: Jiangsu Eye Study.

Purpose: DNA damage is critical in the pathogenesis of age-related cataract (ARC). This study examined the association of copy number variations (CNVs) of DNA repair genes with susceptibility to ARC in the Han Chinese.

Methods: Study participants were from the population-based Jiangsu Eye Study, which includes 780 ARC patients and 525 controls.

The associations between single nucleotide polymorphisms of DNA repair genes, DNA damage, and age-related cataract: Jiangsu Eye Study.

Purpose: Age-related cataract (ARC) is one of the most common causes of severe visual impairment among the elderly worldwide with four subtypes, such as cortical, nuclear, subcapsular, and mixed types. DNA damage and malfunction of DNA repair are believed to contribute to the pathogenesis of ARC. This study examined the associations of 18 single nucleotide polymorphisms (SNPs) in four DNA repair genes (BLM, WRN, ERCC6, and OGG1) with ARC in Han Chinese from the Jiangsu Eye Study, a population-based epidemiologic study.