Carcinogenicity Test of a Copper-Containing Intrauterine Device.

The aim is to study the cellular carcinogenicity of a copper-containing intrauterine device (IUD). So we analyzed the chemical elements of copper-containing IUDs. After that, we used Bhas42 cells in initiation and promotion assays to evaluate the leaching solution that extracted from the copper-containing IUDs at serial dilutions.

[Safety of Alginate-based Gastric Mucosal Protective Adhesive and Feasibility Study of Its Use as Submucosal Injection].

Objective: To study the safety of alginate based gastric mucosal protective adhesive and its feasibility as a submucosal injection.

Methods: The feasibility of using alginate-based gastric mucosal protective gel as submucosal injection was evaluated by gastric mucosal uplift test in pigs and in vivo gastric mucosal uplift test in rats. The safety of alginate based gastric mucosa protective adhesive was evaluated by cytotoxicity test, acute toxicity test and oral mucosa stimulation test according to GB/T 16886 series standard of biological evaluation of medical devices.

[Lung Examination in Systemic Toxicitytest of Medical Devices].

The lung is an important organ in systemic toxicity test of medical devices and is significant in safety evaluation. Based on the authors' understanding of medical devices, this study provides a brief analysis of the lung examination and common problems in systemic toxicity, so as to provide references for the pre-clinical safety evaluation of medical devices. It should be noted that a reasonable risk assessment should be made after comprehensive assessment for specific medical device products.

Carotid artery stiffness in rural adult Chinese: a cross-sectional analysis of the community-based China stroke cohort study.

Objectives: To derive normative carotid artery stiffness data in rural adult Chinese population-based study of ultrasound measurements of carotid elasticity by using quality arterial stiffness (QAS), and to assess the changes of relevant parameters in Chinese adults 40 years of age and older.

Design: A China stroke cohort study (total number: 1586) in the northern countryside were carried out between June 2013 and April 2016, designed to investigate the risk factors of cardiovascular and age-related diseases.

Setting: The present study was a cross-sectional analysis of an ongoing community-based Shunyi cohort study in China.

Removal of cadmium from aqueous solutions using industrial coal fly ash-nZVI.

Batch experiments were conducted to test the effects of various solution properties, such as pH, temperature, initial concentration and anoxic and aerobic atmosphere, on Cd removal by nanoscale zerovalent iron (nZVI) supported on industrial coal fly ash. Cd (II) could be removed by adsorption on fly ash-nZVI in a very short time (5 min) with high removal rates (greater than 99.9%) over a wide range of concentration (5-100 mg l).

Trace metal pollution and carbon and nitrogen isotope tracing through the Yongdingxin River estuary in Bohai Bay, Northern China.

A tide gate was built in 2010 to prevent seawater from moving upstream into the Yongdingxin River estuary in Bohai Bay, Northern China. We analysed the concentrations of Hg, Cd, Pb, TOC, TN, δC and δN and studied their variations in the surface layer and vertical profiles of sediment cores collected from the Yongdingxin River estuary. Contamination factors and geo-accumulation indices were calculated for each metal, which revealed high levels of contamination for Hg and Cd in the sediments, likely from anthropogenic sources.