Publications by authors named "Conghui Deng"

Idiopathic pulmonary fibrosis (IPF) is a chronic and irreversible lung disease, and developing an effective treatment remains a challenge. The limited therapeutic options are primarily delivered by the oral route, among which pirfenidone (PFD) improves pulmonary dysfunction and patient quality of life. However, its high dose and severe side effects (dyspepsia and systemic photosensitivity) limit its clinical value.

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Article Synopsis
  • Fibrosis is a health problem where tissues heal too much, often because of repeated injuries, leading to issues like organ failure and affecting people's lives.
  • While there are some drugs to treat lung fibrosis, like pirfenidone and nintedanib, there aren't any approved drugs for fibrosis in the liver, heart, or kidneys yet.
  • The research focuses on a specific protein called BRD4, which is involved in inflammation and fibrosis, and scientists believe that creating drugs that block BRD4 could help treat fibrosis in the future, though there are still challenges to overcome.
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This data article quantifies the extent of shared bicycle riding risks for shared-bicycle riders in urban China. The data were collected through a WeChat-based online survey, with a valid sample of 1960 respondents. It reports the basic descriptive statistics through eight tables concerning various unsafe shared bicycle riding behaviors, and complete frequency data from riders concerning eight unsafe riding behaviors.

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Shared-bicycle use has skyrocketed in urban China, but little is known about the safety of bicycle users. The Chinese popular media reports multiple risky riding behaviors among shared bicycle riders, but scientific research on the topic is lacking. Therefore, we conducted a retrospective WeChat-based online survey to examine how often shared bicycle riders report engaging in risky cycling behaviors in urban China.

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Anodization is a promising method to change the topography and wettability of titanium (Ti) implant. The formed TiO2 nanotubes (TiNTs) arrays could enhance the biological properties of Ti implants. In this study, to investigate the possibility of TiNTs arrays on a Ti implant surface as nano-reservoirs for small molecular drugs when using in orthopedic and dental prosthesis, TiNTs on a Ti implant surface were prepared.

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