Detectable Virological Load and Associated Factors among People Living with HIV on Antiretroviral Treatment: A Retrospective Study.

The complete and prolonged suppression of viral load is the primary objective of HAART in people living with HIV. Some people may experience therapeutic failure, while others may achieve virological suppression but are unable to maintain it, developing persistent or single detection of low-level viremia. This study aims to evaluate the determinants of a detectable viral load among patients on HAART to identify and address them promptly.

Right to Occupational Safety: Prevalence of Latent Tuberculosis Infection in Healthcare Workers. A 1-Year Retrospective Survey Carried out at Hospital of Lecce (Italy).

Background: Prevention of latent tuberculosis infection (LTBI) in healthcare workers (HCWs) to ensure the "Right to Occupational Safety" is a special challenge globally, as HCWs have a higher risk of acquiring the infection in hospital settings because of frequent close exposure to patients suffering from tuberculosis (TB).

Methods: Aretrospective study was performed with the aim of assessing the prevalence of LTBI related to demographical and occupational risk factors among HCWs employed in a large hospital in Italy. The study involved 1461 HCWs screened for LTBI by Mantoux tuberculin skin test (TST) and then confirmed with Interferon Gamma Release Assay (IGRA) test in case of positivity.

Energy and economic dataset of the worldwide optimal photovoltaic-wind hybrid renewable energy systems.

The data describe supplementary materials supporting the research article entitled "Worldwide geographical mapping and optimization of stand-alone and grid-connected hybrid renewable system techno-economic performance across Köppen-Geiger climates" (Mazzeo et al., 2020). Hybrid renewable energy systems are increasingly adopted worldwide as technically and economically effective solutions to achieve energy decarbonization and greenhouse gas reduction targets.

The first case of sepsis in a non-Hodgkin lymphoma patient: biological understandings and clinical consequencies.

is a rapidly growing nonpathogenic species of the family of bacteria that can cause pulmonary and disseminated disease in particular in immunocompromised individuals. Here we describe a first case of matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass-spectrometry (MS) identification of this pathogen in a patient with non-Hodgkin's lymphoma during chemoimmunotherapy salvage treatment, and its impact on clinical decision making.

Data from a dynamic simulation in a free-floating and continuous regime of a solar greenhouse modelled in TRNSYS 17 considering simultaneously different thermal phenomena.

This dataset supports the research article "Complete greenhouse dynamic simulation tool to assess the crop thermal well-being and energy needs" [1]. In the agricultural sector, the use of energy can be very intensive [2] and the simulation of solar greenhouses is a very complex work [3]. This dataset provides the results of thermal modeling and dynamic simulation of a solar greenhouse considering simultaneously several thermal phenomena.

Technical data of a grid-connected photovoltaic/wind hybrid system with and without storage battery for residential buildings located in a warm area.

Electric production data of a grid-connected hybrid system are presented. The system consists of a photovoltaic generator, a wind micro-generator in the presence (HPWBS) or absence (HPWS) of an electric storage system. In such a system, the power generated by RES (renewable energy sources) is sent directly to balance the load.

Numerical dataset of slab-on-ground floor for buildings in warm climate from a multi-criteria analysis.

This data article relates to a multi-criteria process applied to slab-on-ground floor for buildings in warm climate. The input data of the analysis are the building materials with their thermal properties, sustainability characteristics and supply and installation costs. The multi-criteria analysis has been performed with the software modeFRONTIER.

Operative air temperature data for different measures applied on a building envelope in warm climate.

Several technical combinations have been evaluated in order to design high energy performance buildings for the warm climate. The analysis has been developed in several steps, avoiding the use of HVAC systems. The methodological approach of this study is based on a sequential search technique and it is shown on the paper entitled "Envelope Design Optimization by Thermal Modeling of a Building in a Warm Climate" [1].

Assessment of Serum Vitamin B12 Levels and Other Metabolic Parameters in Subjects With Different Values of Bone Mineral Density.

Background: Controversial experimental and clinical evidences have raised questions regarding the role of B12 and insulin-like growth factor 1 (IGF-1) on osteoblast function and bone health. In this study, we aimed to determine if the serum levels of B12, IGF-1 and procollagen type 1 N-terminal propeptide (P1NP) are associated with different degrees of bone mineral density (BMD).

Methods: A total of 287 subjects (190 women and 97 men; mean age 53 years) volunteered for evaluation of BMD and serum levels of B12, IGF-1 and P1NP; BMD at lumbar spine and proximal femur was evaluated by means of dual-energy X-ray absorption (DEXA) and expressed as T-score; serum concentrations of vitamin B12 and IGF1 were measured with a chemiluminescent immunoassay on Access II Beckman Coulter and DiaSorin Liaison XL analyzers, respectively; P1NP was assessed in 61 women and 35 men with reduced T-score on Roche Modular platform.

Data of cost-optimal solutions and retrofit design methods for school renovation in a warm climate.

"Efficient Solutions and Cost-Optimal Analysis for Existing School Buildings" (Paolo Maria Congedo, Delia D'Agostino, Cristina Baglivo, Giuliano Tornese, Ilaria Zacà) [1] is the paper that refers to this article. It reports the data related to the establishment of several variants of energy efficient retrofit measures selected for two existing school buildings located in the Mediterranean area. In compliance with the cost-optimal analysis described in the Energy Performance of Buildings Directive and its guidelines (EU, Directive, EU 244,) [2], [3], these data are useful for the integration of renewable energy sources and high performance technical systems for school renovation.

Data on external walls from a multi-objective simulation for cold climates.

Data are related to the multi-objective optimization process applied to the building materials to obtain high energy-efficient precast walls for cold climate. The methodology has been explained on the paper entitled "High performance precast external walls for cold climate by a multi criteria methodology" (Baglivo and Congedo, 2016) [1]. The modeFRONTIER rel.

Data on Support Vector Machines (SVM) model to forecast photovoltaic power.

The data concern the photovoltaic (PV) power, forecasted by a hybrid model that considers weather variations and applies a technique to reduce the input data size, as presented in the paper entitled "Photovoltaic forecast based on hybrid pca-lssvm using dimensionality reducted data" (M. Malvoni, M.G.

Data resulting from the CFD analysis of ten window frames according to the UNI EN ISO 10077-2.

Data are related to the numerical simulation performed in the study entitled "CFD modeling to evaluate the thermal performances of window frames in accordance with the ISO 10077" (Malvoni et al., 2016) [1]. The paper focuses on the results from a two-dimensional numerical analysis for ten frame sections suggested by the ISO 10077-2 and performed using GAMBIT 2.

Data on photovoltaic power forecasting models for Mediterranean climate.

The weather data have a relevant impact on the photovoltaic (PV) power forecast, furthermore the PV power prediction methods need the historical data as input. The data presented in this article concern measured values of ambient temperature, module temperature, solar radiation in a Mediterranean climate. Hourly samples of the PV output power of 960kWP system located in Southern Italy were supplied for more 500 days.

High performance solutions and data for nZEBs offices located in warm climates.

This data article contains eleven tables supporting the research article entitled: Cost-Optimal Design For Nearly Zero Energy Office Buildings Located In Warm Climates [1]. The data explain the procedure of minimum energy performance requirements presented by the European Directive (EPBD) [2] to establish several variants of energy efficiency measures with the integration of renewable energy sources in order to reach nZEBs (nearly zero energy buildings) by 2020. This files include the application of comparative methodological framework and give the cost-optimal solutions for non-residential building located in Southern Italy.

Targeting candidates for directly administered highly active antiretroviral therapy: benefits observed in HIV-infected injecting drug users in residential drug-rehabilitation facilities.

The purpose of this study was to evaluate retrospectively the potential benefits of directly administered antiretroviral therapy (DAART) in HIV-infected former injecting drug users (ex-IDUs) admitted to residential drug rehabilitation facilities. We compared 106 of these patients consecutively admitted in 12 communities where DAART was administered (DAART group) to two matched control groups of ex-IDUs undergoing self-administered ART: 106 subjects in other 10 communities (SAT group) and 106 outpatients at hospital infectious-disease wards where community patients were referred after discharge (OUT group). We estimated the proportion of patients with high adherence and the hazard ratio (HR) of 20% or more increase in the CD4(+) cell count and of reaching an undetectable viral load.

Diagnosis of bacteriuria and leukocyturia by automated flow cytometry compared with urine culture.

Urinary tract infection (UTI) is a widespread disease, and thus, the most common samples tested in diagnostic microbiology laboratories are urine samples. The "gold standard" for diagnosis is still bacterial culture, but a large proportion of samples are negative. Unnecessary culture can be reduced by an effective screening test.

Giardiasis in HIV: a possible role in patients with severe immune deficiency.

We report the epidemiological, clinical and therapeutic characteristics of giardiasis in a population of HIV-infected patients with diarrhoic syndrome. During the period between 1988 and 1995, 720 HIV-patients with diarrhoic syndrome were evaluated. Fecal specimens were submitted to parasitological examination according to the Ritchie formalin-ethil acetate centrifugal sedimentation method and stained with iodine.

Efficacy of itraconazole in treating AIDS-associated infections due to Candida krusei.

Candida krusei is an emerging pathogen, both in HIV negative immunocompromised patients and in HIV seropositive patients. Its onset appears to be due, at least in part, to the use of fluconazole. In HIV positive patients, a long term prophylactic use of fluconazole may select some less pathogenic Candida species, as C.

Early abnormalities of the antibody response against Mycobacterium tuberculosis in human immunodeficiency virus infection.

Among human immunodeficiency virus (HIV)-infected persons, those who react against purified protein derivative (PPD) have higher risk of tuberculosis. Since PPD testing has limited predictive power in HIV-positive populations, new markers of antituberculous immunity were sought by analyzing antibodies to Mycobacterium tuberculosis antigens (PPD and its fraction A60) in 102 HIV-positive subjects, some PPD-positive and some PPD-negative, and in 23 HIV-positive tuberculosis patients. ELISA and Western blotting were used.

In vitro production of HIV-1 specific antibodies from "at risk" seronegative subjects.

We investigated a group of well characterized seronegative subjects "at risk" for HIV-1 infection including heterosexual partners of HIV-1 infected subjects and intravenous drug abusers. Pokeweed mitogen (PWM)-stimulated peripheral blood mononuclear cells (PBMCs) were studied for their ability to produce antibodies against HIV-1 structural proteins in vitro. Viral activity by means of HIV-1 isolation from PBMCs and presence of serum p24 antigen were also tested.