One new sterpurane sesquiterpene (), named (3,6,7,8,10)-3,7,14-trihydroxy-1-sterpurene was isolated from cultures of the basidiomycete The structure of new compound was elucidated by extensive spectroscopic. Additionally, a single crystal X-ray diffraction not only confirmed the structure, but also determined the absolute configuration of the new compound. The compound was evaluated for cytotoxicity against five human cancer cell lines, but no significant cytotoxicity were found (IC values > 40 μM).
View Article and Find Full Text PDFObjective: To investigate the specific biotransformation product of ginsenoside Rb1 of Panax notoginseng saponins( PNS) by an individual plant endophyte.
Methods: The endophytes of an invasive plant were selected as the screening targets of active conversion strains. The chromatography and high performance liquid chromatography were used to detemine the metabolite.
Objective: To develop an HPLC method for simultaneous determination of notoginsenoside R₁ and ginsenosides Rg₁ Re, Rh₁, Rb₁, Rd, Rk₃, Rh₄, 20(S)-Rg₃ and 20(R)-Rg₃ in raw and steamed Panax notoginseng root and rhizome.
Methods: Vision HT C18 column (250 mm x 4.6 mm, 5 µm) was used with the mobile phase consisted of acetonitrile-H₂O in a gradient elution mode at the flow rate of 1.
Ginseng saponins are a type of important active substances in the ginseng genus plants. They have notable pharmacological activities of antineoplastic, neuroprotective, and hepatoprotective activities, which have been drawn more attention to obtain minor ginsenosides by all kinds of methods. In this review, we discussed the latest progress for enrichment of minor ginsenosides by biological transformation of major ginsenosides.
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