[Heteroplasmy in human mtDNA control region].

Objective: To observe the length heteroplasmy and point heteroplasmy in human mtDNA control region.

Methods: The peripheral blood, buccal cell, and single hair shaft from 50 individuals and 16 family members, related in their maternallineage were analyzed by direct sequencing, and clones from 20 individuals whose mtDNA sequences have a T-C transition at 16189 nt were sequenced.

Results: No point heteroplasmy were observed in peripheral blood, buccal cell, single hair shaft from the same individual, neither in maternally related individuals.