[Expression level and effect of P2X7 receptor mRNA during osteogenic differentiation of human periodontal ligament stem cells].

Purspose: To investigate the role of P2X7 receptor in osteogenic differentiation of human periodontal ligament stem cells.

Methods: Human periodontal ligament stem cells obtained from primary culture were divided into 4 groups: control group, adenosine triphosphate group, osteogenic induction group, adenosine triphosphate + osteogenic induction group. The differences of RUNX2, OCN gene expression and P2X7 receptor mRNA expression between the four groups were compared.