Minor protopanaxadiol type sapogenins from the alkali hydrolysate of stems-leaves of .

Two new protopanaxadiol type sapogenins, (3,12)-3,12,20-trihydroxydammar-24-en-26-al () and (3,12)-3,12,20-trihydroxydammar-24-en-26-oic acid (), were isolated from the alkali hydrolysate of stems-leaves of , along with seven known analogues (-). Their structures were elucidated by spectroscopic analyses and single-crystal X-ray diffraction. Compound and the known sapogenins - displayed weak to moderate inhibition of NO production in LPS-induced RAW264.

A Study of Machine-Learning Classifiers for Hypertension Based on Radial Pulse Wave.

Objective: In this study, machine learning was utilized to classify and predict pulse wave of hypertensive group and healthy group and assess the risk of hypertension by observing the dynamic change of the pulse wave and provide an objective reference for clinical application of pulse diagnosis in traditional Chinese medicine (TCM).

Method: The basic information from 450 hypertensive cases and 479 healthy cases was collected by self-developed H20 questionnaires and pulse wave information was acquired by self-developed pulse diagnostic instrument (PDA-1). H20 questionnaires and pulse wave information were used as input variables to obtain different machine learning classification models of hypertension.

Tongue Image Database Construction Based on the Expert Opinions: Assessment for Individual Agreement and Methods for Expert Selection.

This study aims at introducing a method for individual agreement evaluation to identify the discordant raters from the experts' group. We exclude those experts and decide the best experts selection method, so as to improve the reliability of the constructed tongue image database based on experts' opinions. Fifty experienced experts from the TCM diagnostic field all over China were invited to give ratings for 300 randomly selected tongue images.