Superior Temperature Sensing and Capacitive Energy-Storage Performance in Pb-Free Ceramics.

The ultrafast charge/discharge rate and high power density (P) endow lead-free dielectric energy storage ceramics (LDESCs) with enormous application potential in electric vehicles. However, their low energy storage density and single energy storage performance (ESP) limit their further development and applicability in rugged environments. Here, through the design of vacancy defects and phase structure regulation, Pb-free (BiNa)TiO-based ceramics with an optimal composition can achieve a large maximum polarization (>44 µC cm) under a moderate electric field (410 kV cm), resulting in an extremely high recoverable energy storage density (≈6.

Determination of the relationship between the numbers of Linepithema humile (Hymenoptera: Formicidae) on irrigation pipes and tree trunks to facilitate automated monitoring in Southern California citrus orchards.

Argentine ant, Linepithema humile (Mayr) (Hymenoptera: Formicidae), is a pest in southern California citrus orchards because it protects honeydew-producing hemipteran pests from natural enemies. A major impediment to controlling L. humile is estimating ant densities in orchards.

Case report: Vein of Marshall-catheter ablation combined with left atrial appendage occlusion for treatment of atrial fibrillation.

The utilization of the one-stop strategy for treating atrial fibrillation (AF) has been on the rise, but the combination of vein of Marshall catheter ablation with left atrial appendage occlusion has been rarely reported. In this case, a 62-year-old man with persistent AF underwent a one-stop strategy that included ethanol infusion in the vein of Marshall, radiofrequency catheter ablation, and left atrial appendage occlusion. The procedures successfully achieved ablation in the vein of Marshall, pulmonary vein isolation, and left atrial appendage occlusion.

Utilization of Three-Dimensional Electron Diffraction for Structure Determination of Extra-Large-Pore Zeolites.

The development of extra-large-pore (ELP) zeolites is crucial for industries of petrochemical catalysis, notably in processes like diesel cracking and hydrocracking of multi-carbon hydrocarbon substrates. The catalytic performance and selectivity of these zeolites depend heavily on their specific porous structures, making precise structure determination highly essential for understanding their properties and functionalities. However, the complex structures of ELP zeolites pose significant challenges for characterization.

Mapping grey matter and cortical thickness alterations associated with subjective cognitive decline and mild cognitive impairment among rural-dwelling older adults in China: A population-based study.

Background: The structural brain alterations for subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are poorly defined. We sought to characterize grey matter volume (GMV) and cortical thickness associated with SCD and MCI among rural-dwelling older adults in China.

Methods: This population-based cross-sectional study included 1072 dementia-free participants from the brain MRI sub-study of MIND-China (2018-2020).

Dimethylsulfoniopropionate (DMSP) Increases Longevity and Mitochondrial Function in : Implications for the Role of the Global Sulfur Cycle in Terrestrial Ecosystems.

Dimethylsulfoniopropionate (DMSP) is a compound synthesized by marine phytoplankton that contributes to the oceanic sulfur cycle. Interestingly, DMSP has also been found in algal species and several terrestrial plants, forming part of the global sulfur cycle. However, compared to its role in the marine environment, the impact of DMSP on terrestrial ecosystems remains relatively unexplored.

Long-term Nerve Regeneration in Diabetic Keratopathy Mediated by a Novel NGF Delivery System.

Diabetic keratopathy (DK) is a common chronic metabolic disorder that causes ocular surface complications. Among various therapeutic approaches, local delivery of nerve growth factor (NGF) remains the most effective treatment of DK. However, achieving a sustained therapeutic effect with NGF and the frequent drug delivery burden remain challenging during clinical practice.

Preventing and treating neurotrophic keratopathy by a single intrastromal injection of AAV-mediated gene therapy.

Purpose: Neurotrophic keratopathy (NK) is a degenerative corneal condition resulting from corneal nerve injury. Current therapies, including the recombinant human nerve growth factor (rhNGF) therapy, requires continuous administration. This study aims to develop a novel and highly effective gene therapy strategy for the prevention and treatment of NK.

Photoconductivity and Photovoltaic Effect Strengthened via Microstructural Cotuning in Ferroelectrics: Intuitively Assessed by Macroscopic Transparency.

Photoferroelectrics that involve strong light-matter coupling are regarded as promising candidates for realizing bulk photovoltaic and photoelectric effects via light absorption. Nonetheless, understanding the photoresponse mechanism or modulation of performance from a microscopic point of view is scarcely explored through quantification of macroscopic properties. Herein, we design a model material, Gd-doped (KNa)NbO ferroelectric-transparent ceramics, and present an advantageous strategy to enhance the optoelectronic coupling through joint modulations of lattice distortion and oxygen vacancies, along with inner defects and ferroelectric domains.

Association of dementia with impaired kidney function and plasma biomarkers: A population-based study.

Background And Purpose: Emerging evidence has linked impaired kidney function with dementia in older adults, but the neuropathological pathways underlying their association remain poorly understood. We sought to examine the relationships of kidney function with dementia and plasma biomarkers in a Chinese rural population.

Methods: This population-based study used data from the baseline examination of the Multimodal Interventions to Delay Dementia and Disability in rural China (MIND-China) cohort (March-September 2018; n = 5715).

[Identification and characterization of a novel polyamide hydrolase].

The widespread use of non-naturally degradable plastics is causing increasingly serious harm to the environment. Reducing plastic pollutants has become the core of ecological and environment management. Biological methods such as enzymes demonstrate advantages in depolymerizing plastics with mild reaction conditions and recycling of depolymerization products.

Giant Capacitive Energy Storage in High-Entropy Lead-Free Ceramics with Temperature Self-Check.

Considering the large demand for electricity in the era of artificial intelligence and big data, there is an urgent need to explore novel energy storage media with higher energy density and intelligent temperature self-check functions. High-entropy (HE) ceramic capacitors are of great significance because of their excellent energy storage efficiency and high power density (P). However, the contradiction between configurational entropy and polarization in traditional HE systems greatly restrains the increase in energy storage density.

Depression exacerbates myocardial ischemia-reperfusion injury in mice via CNR2 gene and MIF-AMPK signaling pathway.

Background: Myocardial ischemia-reperfusion(I/R)injury constitute the fundamental pathophysiology of acute myocardial infarction (AMI). Ischemic heart releases macrophage migration inhibitory factor (MIF), which activates MIF- AMPK signaling pathway. Depression is a significant risk factor for AMI.

Anti-inflammatory effects of MerTK by inducing M2 macrophage polarization via PI3K/Akt/GSK-3β pathway in gout.

Mer tyrosine kinase (MerTK) has been found to regulate the secretion of inflammatory factors and exert immunosuppressive effects, but its role in gout remains unclear. In this study, we aimed to clarify the immnue effects of MerTK in gout. MerTK in synovium or serum of gout patients was determined by immunohistochemistry, enzyme-linked immunosorbent assay (ELISA), and real-time quantitative polymerase chain reaction (RT-qPCR).

Synergistic associations of CD33 variants and hypertension with brain and cognitive aging among dementia-free older adults: A population-based study.

Introduction: CD33 rs3865444 and hypertension (HTN) are related to cognitive impairment, individually. However, little is known about their combined effects on cognitive function in older adults.

Methods: This population-based study included 4368 dementia-free participants (age ≥65 years) in the Multimodal Interventions to Delay Dementia and Disability in Rural China (MIND-China), with data available in 1044 persons for gray matter volume and 85 persons for cerebral blood flow (CBF).

The paravertebral lymphatic system is involved in the resorption of the herniated nucleus pulposus and the regression of inflammation associated with disc herniation.

Objective: To investigate the role of the paravertebral lymphatic system in the nucleus pulposus herniation (NPH) resorption and the inflammation regression.

Design: Clinical specimens (n = 10) from patients with lumbar disc herniation (LDH) were collected, C57BL/6 (n = 84) and conditional Vegfr3 knockout mice (n = 14) were used. Immunofluorescence staining detected lymphatic vessels (LVs) and NP cells.

CT imaging-based nomogram for predicting early-stage glottic cancer recurrence following transoral laser microsurgery.

Objective: To explore the differences between clinical features and computed tomography (CT) findings of early-stage glottic cancer (EGC) with or without recurrence after transoral laser microsurgery (TLM) and to establish a preoperative nomogram to predict postoperative recurrence.

Methods: The clinical and CT features of 168 consecutive patients with EGC with or without recurrence were analyzed retrospectively. Multivariate logistic regression analysis was used to determine the independent predictors of recurrence.

Association of polygenic risk scores with Alzheimer's disease and plasma biomarkers among Chinese older adults: A community-based study.

Introduction: We examined the associations of polygenic risk score (PRS) with Alzheimer's disease (AD) and plasma biomarkers in the Chinese population.

Methods: This population-based study used baseline data from MIND-China (2018; n = 4873) and follow-up data from dementia-free individuals (2014-2018; n = 2117). We measured AD-related plasma biomarkers in a subsample (n = 1256).