[Aseptic osseous necrosis after renal transplantation].

Of 165 renal Transplantated patients, 12 developed aseptic bone necrosis in the femoral head (6 patients), in the femoral condyle (5 patients), in the astragalus (1 patient). The onset of symptoms was 6 to 23 months after transplantation. 99mTc-O4-MDP bone scintigraphy and radiological examination associated with clinical signs confirmed the diagnosis.

[Diagnosis and therapy of lymphocele as a complication of renal transplantation].

Of 165 renal transplanted patients, three (1.8%) developed a pelvic lymphocele. Decreased renal function, leg edema, a lower quadrant abdominal mass and fluid retention represented suspicion as the possibility of lymph collection in the perirenal space.

[HLA and rejection of renal transplants from cadavers].

Seventy-two patients were typed for HLA-A and HLA-B. Kidney-graft survival, reversibility and time of appearance of reject episodes were comparated with matching level. Matching level had double classification: NIT and Verona; the validity of tissue-typing as prediction of the best result of transplantation and major reversibility of reject episodes.

[Significance of mixed lymphocyte culture (MLC) in renal transplants from living donors].

Results of MLC were correlated with kidney-graft survival of recipients of living related donor. The 56 patients tested by MLC were divided into two groups according as the stimulation index was more or less than 5. In 20 of these patients transplanted, renal allograft survival correlated better with low stimulation in MLC, suggesting more histocompatibility.

[Relation between cytomegalovirus infection and the so-called intolerance to azathioprine in renal transplantation].

Renal transplant recipients can develop hepatic function abnormalities or severe leucopenia after transplantation. Generally it is thought to be due to azathioprine intolerance and patients are treated by curtailment of immunosuppressive therapy, being subsequently at risk to lose their allograft because of rejection. Evidence of Cytomegalovirus (CMV) infection is also common after renal transplantation.

Serum gastrin levels in patients with renal failure on maintenance haemodialysis and after successful kidney transplantation.

Chronic renal failure in man is associated with a hypergastrinaemia which is not corrected by haemodialysis. Serum gastrin concentrations were measured in 66 patients on maintenance haemodialysis and in 27 patients after successful kidney transplantation. The basal gastrin levels distinguished 2 groups of patients on maintenance haemodialysis: a first group with gastrin values less than or equal to 120 pg/ml (mean 58+/-29.