Fibroadenoma in axillary supernumerary breast: case report.

Context: Supernumerary breast tissue may be affected by the same diseases and alterations that compromise topical breast tissue. Nevertheless, reports of fibroadenoma in supernumerary breast tissue in the axillae are rare.

Objective: To describe a case of fibroadenoma in an axillary supernumerary breast.

Quality of life in Brazilian breast cancer survivors age 45-65 years: associated factors.

The objectives of this study were to evaluate quality of life (QOL) and identify its associated factors in climacteric women with a history of breast cancer. A cross-sectional study was performed including 75 breast cancer survivors age 45-65 years who had undergone complete oncologic treatment and nonusers of hormone therapy or tamoxifen in the last 6 months. Sociodemographic and clinical characteristics in addition to the prevalence of climacteric symptoms were evaluated.

Menopause symptoms and quality of life in women aged 45 to 65 years with and without breast cancer.

Objective: To compare the prevalence of menopause symptoms, sexual activity, and quality of life in women with and without breast cancer.

Design: A cross-sectional study using one group for comparison was conducted on women aged 45 to 65 years who had not received hormone therapy or tamoxifen during the last 6 months. Participants were recruited from the Menopause and Breast Cancer Outpatient Facilities.

[Quality of life in users and non-users of hormone replacement therapy].

Objective: To compare the quality of life in postmenopausal women who were users and non-users of hormone replacement therapy (HRT).

Methods: A cross-sectional study was conducted on postmenopausal women aged between 40 and 65 years, who had been menopausal for up to 15 years. Women considered HRT users were those who had undergone this type of treatment for at least six months.

[Prevalence and factors associated with intestinal constipation in postmenopausal women].

Background: Constipation occurs more frequently in the female population and it becomes more prevalent with increasing age. There are few studies that have assessed the prevalence of constipation in postmenopausal women.

Aim: To investigate the prevalence and factors associated with constipation in postmenopausal women.

Impact of the preservation of the intercostobrachial nerve in axillary lymphadenectomy due to breast cancer.

This study evaluated the relationship between preservation of the intercostobrachial (ICB) nerve and pain sensitivity of the arm, the total time of the surgery, and the number of dissected nodes in patients submitted to axillary lymphadenectomy due to breast cancer. An intervention, prospective, randomized, and double blind study was performed on 85 patients at the State University of Campinas, Brazil, from January 1999 to July 2000. The patients were divided into two groups, according to whether the ICB nerve was preserved or not.

Acute ethanol administration reduces the cognitive deficits associated with traumatic brain injury in rats.

The present study was designed to determine whether a low dose of acute ethanol administration could attenuate cognitive deficits associated with traumatic brain injury. Adult male rats received oral administration of ethanol or drinking water 2 h prior to surgery to produce a blood ethanol concentration of 100 mg% and then received bilateral contusion injuries of the medial prefrontal cortex. Seven days after surgery, the rats began 10 days of testing for acquisition of spatial localization in the Morris water maze where they were required to find a hidden platform to escape from the water.

Effect of amiodarone and propranolol on the functional properties of human thyroid follicles cultured in collagen gel.

Amiodarone and propranolol have been known to inhibit the peripheral conversion of thyroxine (T4) to 3,5,3'-triiodothyronine (T3) but their direct effect on the thyroid gland is not understood. We therefore investigated the action of the two drugs on the functional properties of human thyroid follicles embedded in collagen gel. Amiodarone and propranolol induced a dose-dependent reduction or blocking of the follicular production of cyclic AMP (cAMP), thyroglobulin (Tg) and free triiodothyronine (FT3) under 200 microU/ml medium.

Functional properties of human thyroid follicles cultured within collagen gel.

Cultures of human thyroid follicles embedded in collagen gel were performed to investigate certain functional properties under bovine thyrotropin (TSH) stimulation. Follicles obtained from normal glands responded to increasing concentrations of TSH administered on day 4 in culture and for 3 days by increased amounts of cyclic AMP (cAMP), thyroglobulin (Tg) and triiodothyronine (T3) and by decreased levels of thyroxine (T4). Effect was maximal at 2000 microU/ml TSH (cAMP) or 200 microU/ml (Tg, T3, T4).