Publications by authors named "Concha-Velasco Fatima"
Subcapsular Liver Hematoma: One of the Many Faces of Acute Fascioliasis.
Open Forum Infect Dis
October 2024
Subcapsular liver hematoma is an uncommon and underdiagnosed manifestation of fascioliasis. We report 6 cases and review 21 previous reports. The mean age was 51 years; 12 cases were from Peru; and 18 were women.
View Article and Find Full Text PDFArticle Synopsis
- The study examined the clinical and epidemiological characteristics of 7 Peruvian patients who were infected with HTLV-1 and cryptococcosis, while being negative for HIV.
- Most of the patients had meningeal involvement, were male, and came from the jungle regions of Peru.
- The findings suggest that individuals with cryptococcosis in areas where HTLV-1 is common should be routinely tested for this retrovirus.
Background: The spread of the coronavirus disease 2019 (COVID-19) in Peru has been reported at the regional level, few studies have evaluated its spread at the provincial level, in which the mechanisms could be different.
Methods: We conducted an analytical, cross-sectional, multistage observational population study to assess the seroprevalence of SARS-COV-2 at the provincial and urban/rural levels in a high-altitude setting. The sampling unit was the household, including a randomly selected family member.
Background: Peru reports higher levels than other countries in Latin America of resistance to antimicrobials among Gram-positive and Gram-negative bacteria, however data on antibiotic use in Peru are scarce. This study aims to estimate the prevalence and quality of antibiotic prescription in hospitalized patients and to determine the antibiotic susceptibility rates of bacteria causing key bacterial infections.
Methods: We carried out a point prevalence survey of antibiotic prescription at ten public hospitals in nine regions of Peru.
There is a knowledge gap in the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) causing bloodstream infections (BSIs) in Peru. Through a surveillance study in 13 hospitals of 10 Peruvian regions (2017-2019), we assessed the proportion of MRSA among S. aureus BSIs as well as the molecular typing of the isolates.
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- A study was conducted in 15 hospitals across Peru from July 2017 to October 2019 to collect data on antimicrobial resistance in gram-negative bacteria (GNB), as existing data was lacking.
- Out of 449 collected blood culture isolates, 59.2% showed resistance to third-generation cephalosporins, and 16.5% displayed carbapenem resistance, with significant variations among different bacterial species.
- The study found that 63.3% of empiric treatments effectively covered the causative GNB, but the in-hospital death rate was high at 33.3%, particularly linked to Pseudomonas aeruginosa and carbapenem-resistant infections.
We reported an outbreak of wild rabies in (choznas), a carnivorous mammal associated with insectivorous bats in Kosñipata, Cusco, Peru, from February 2021 to October 2022. Eight human exposures were reported, with aggressive attacks resulting in injuries. The outbreak prompted a public health response and raised concerns about zoonotic diseases due to habitat fragmentation and urbanization.
View Article and Find Full Text PDFFactors Associated with COVID-19 Death in a High-Altitude Peruvian Setting during the First 14 Months of the Pandemic: A Retrospective Multicenter Cohort Study in Hospitalized Patients.
Trop Med Infect Dis
February 2023
Article Synopsis
- The study investigated COVID-19 death risk factors in high-altitude populations, specifically in Cusco, Peru, during the early months of the pandemic.
- Approximately 50% of adult patients (1225 out of 2674) who died in three hospitals were analyzed, with 977 confirmed to have died from COVID-19.
- Key findings indicated that critical disease increased the risk of death, while ICU admission, invasive respiratory support, and specific oxygenation metrics were associated with lower mortality, which could help in healthcare decision-making.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage C.37 (Lambda) has spread rapidly in Peru and other Latin American countries. However, most studies in Peru have focused on Lima, the capital city, without knowing the dynamics of the spread of the variant in other departments.
View Article and Find Full Text PDFUrinary tract infections (UTIs) are a common human infection. Antibiotic resistance in extended-spectrum β-lactamase (ESBL)-producing uropathogenic (UPEC) is a major therapeutic challenge due to limited treatment alternatives. The aim was to characterize the antimicrobial resistance (AMR) and dynamics of ESBL-producing UPEC isolates from UTI cases seen at a local hospital in Cusco, Peru.
View Article and Find Full Text PDFIntroduction: The first-line combination therapy for HIV-associated cryptococcal meningitis (CM), a condition of high mortality particularly in the first two weeks of treatment, consists of amphotericin B plus flucytosine (5-FC). Given that 5-FC remains unavailable in many countries, the knowledge of factors influencing mycological clearance in patients treated with second-line therapy could contribute to effective management.
Objectives: To determine the factors associated with the clearance of Cryptococcus sp.