Publications by authors named "Conceicao de Maria Pedrozo E Silva de Azevedo"

Objective: To describe an outbreak due to Candida vulturna, a newly emerging Candida species belonging to the Candida haemulonii species complex in the Metschnikowiaceae family.

Methods: In this retrospective cohort study we genotyped 14 C. vulturna bloodstream isolates, occurring in a 4-month-period in paediatric cancer patients in a Brazilian hospital.

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Chromoblastomycosis, an implantation mycosis, is a neglected tropical disease that causes decreased quality of life, stigma, and disability. The global burden of disease is unknown and data on disease epidemiology and outcomes are severely limited by a lack of access to needed diagnostic tools and therapeutics. The World Health Organization outlined targets for chromoblastomycosis in the Road Map for Neglected Tropical Diseases 2021-2030, but little progress has been made in initiating and implementing an effective control program globally.

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Article Synopsis
  • Orally transmitted acute Chagas disease (ACD) is a significant global health issue, especially affecting low-income populations in tropical areas, and presents management challenges even after over 100 years of recognition.
  • A reported outbreak in Pedro do Rosário, Brazil, involved 39 ACD cases linked to bacaba juice, highlighting the need for thorough clinical and epidemiological investigations; diagnostic success varied significantly based on the criteria used.
  • The study found considerable obstacles in ACD management, including outdated diagnostic methods, reliance on conventional treatments, and the vulnerability of affected populations, emphasizing the need for better diagnostic and therapeutic strategies.
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Background: In Brazil, Leishmania (Leishmania) infantum is a widely distributed protozoan parasite. The human leishmaniasis caused by this species is often associated with visceral form. Tegumentary leishmaniasis (TL) cases due to L.

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Article Synopsis
  • A case of extensive human cutaneous protothecosis was reported in northeastern Brazil, diagnosed through skin sample examination and culture on Sabouraud dextrose agar.
  • Initial treatment with itraconazole was unsuccessful, but switching to liposomal amphotericin followed by voriconazole led to a clinical cure.
  • Prothotecosis should be considered as a possible diagnosis for skin lesions that appear after trauma, especially if they evolve atypically.
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Visceral leishmaniasis (VL) is a potentially fatal disease caused mainly by Leishmania infantum in South America and Leishmania donovani in Asia and Africa. Disease outcomes have been associated with patient genotype, nutrition, age, sex, comorbidities, and coinfections. In this study, we examine the effects of parasite genetic variation on VL disease severity in Brazil.

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Background: Chromoblastomycosis (CBM), represents one of the primary implantation mycoses caused by melanized fungi widely found in nature. It is characterized as a Neglected Tropical Disease (NTD) and mainly affects populations living in poverty with significant morbidity, including stigma and discrimination.

Methods And Findings: In order to estimate the global burden of CBM, we retrospectively reviewed the published literature from 1914 to 2020.

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Objective: To estimate the seroprevalence of SARS-CoV-2 in the state of Maranhão, Brazil.

Methods: A population-based household survey was performed, from July 27, 2020 to August 8, 2020. The estimates considered clustering, stratification and non-response.

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Chromoblastomycosis is a chronic, cutaneous or subcutaneous mycosis characterized by the presence of muriform cells in host tissue. Implantation disease is caused by melanized fungi related to black yeasts, which, in humid tropical climates, are mainly members of the genus . In endemic areas of Brazil, and are the prevalent species.

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Chromoblastomycosis (CBM) is a neglected implantation mycosis prevalent in tropical climate zones, considered an occupational disease that affects impoverished rural populations. This retrospective study described clinical aspects of CBM in a hyperendemic area in Brazil and constructed a worldwide haplotype network of spp. strains.

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Diffuse cutaneous leishmaniasis (DCL) is a rare type of leishmaniasis characterized by diffuse skin lesions. In Brazil, () is the main etiological agent of this clinical form. The state of Maranhão has the highest prevalence of this disease in the country, as well as a high rate of HIV infection.

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Article Synopsis
  • Chromoblastomycosis is a neglected infectious disease that mainly affects rural workers through skin lesions caused by fungi from contaminated soil and plants.
  • The study examined the role of social insects like ants, bees, and termites as potential habitats for the disease-causing fungi, identifying several fungal strains associated with these insects.
  • Pathogenicity tests on these fungi showed that they can cause disease in animal models, revealing their ability to persist in host tissues.
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Objective: To analyze the results of the audiological evaluation of children with HIV and AIDS.

Data Collection: Systematic review carried out in May 2019 in the Web of Science, PubMed, SciELO, and Scopus databases. Case reports and original articles were included, with no limitationsregarding country or year of publication.

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Background: The aim of this study was to compare cases of Visceral Leishmaniasis (VL) with and without HIV in a state in northeastern Brazil.

Methodology: We performed a comparative study in the state's referral hospital for infectious/parasitic diseases located in Northeast Brazil between January 2007 and July 2017. The data obtained using this protocol were analyzed with SPSS.

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Waterborne outbreaks of human toxoplasmosis can have great magnitude due to the number of persons infected while smaller-scale outbreaks are also possible. This is a study based on a historical database investigating a toxoplasmosis outbreak occurred in 2006 in a residential community in São Luís, in the Brazilian state of Maranhão. Ninety of the 110 residents, employees and domestic helping persons had blood samples collected and tested.

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  • Climate significantly affects human health, particularly in terms of hospitalizations for mycoses in Brazilian state capitals from 2008 to 2016.
  • Minimum temperature was identified as a critical factor influencing hospitalizations, with variations observed between annual and monthly time scales.
  • Mycoses hospitalizations peaked during La Niña events and decreased during El Niño events, indicating a complex relationship between regional and global climate influences on disease prevalence in Brazil.
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