Analysis of the protease sequences of HIV-1 infected individuals after Indinavir monotherapy.

Background: Protease inhibitors (PI) are an important HIV-1 treatment tool. The HIV-1 genetic diversity as a result of antiretroviral exposure is a potential barrier to successful antiretroviral therapy.

Objectives: To describe the impact of the selective pressure of the PI Indinavir in the protease region of the pol gene of HIV-1.