Publications by authors named "Conard R"

Background: Known barriers to family planning in the transgender population include low utilization of cryopreservation and decisional regret. There is growing data on the risk of infertility with GAHT, and on to what degree transgender adolescents feel informed about fertility and family planning options.

Objective: Assess preferences regarding options for family planning and fertility preservation in transgender adolescents treated with GAHT in a pediatric endocrinology gender clinic.

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Objectives: Nursing home (NH) Minimum Data Set (MDS) have frequently been used to measure medication use in epidemiologic studies, but there is little evidence on the accuracy of MDS-based medication records. We compared antipsychotic use estimated using 2 data sources-MDS and NH electronic medication administration records (eMAR).

Design: Cross-sectional comparison.

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Despite advances in antiretroviral treatment (ART), the HIV epidemic persists in the United States (U.S.), with inadequate adherence to treatment and care a major barrier to ending the epidemic.

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Objective: To determine if a history of aggressive/impulsive behavior adversely affected the return to full duty of a military psychiatric inpatient population.

Method: Charts were reviewed for aggressive/impulsive behavior as indicated by self-report on a standardized admission form and by history in 211 consecutive admissions pooled from two separate 2-month intervals during a 9-month period.

Results: Seventy-three percent of the population was between the ages of 17 and 24 years.

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The events prior to Bravo Shot-Operation Castle that led to a decision not to evacuate the Marshallese prior to testing the thermonuclear bombs are presented as are the actions taken after the fallout incident in evacuating the exposed Marshallese and the military personnel. The initial medical effects (findings during first 6 wk after exposure) are briefly described and are followed by description of long term effects, namely, induction of one case of fatal acute myeloid leukemia and a large number of thyroid tumors (benign and malignant) in addition to hypothyroidism in adults and children and two cases of cretinism. The hypothyroidism and cretinism responded well to administration of oral thyroxine.

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On March 1, 1954, after detonation of a thermonuclear device on Bikini atoll, an unexpected wind shift resulted in the deposition of radioactive fallout on inhabited atolls. The fallout radiation caused fleeting systemic effects, dose-dependent depression of hematopoiesis and skin burns primarily due to the beta ray component of the fission radionuclides. Within a few weeks, hematopoietic recovery was substantial but slight depression of blood counts was maintained for several years.

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The fiberglass-reinforced plastics industry and the literature on controlling exposures to toxic substances were surveyed to select work practices and housekeeping conditions that might be useful in reducing workers' exposures to styrene. A training program was developed to teach the selected behaviors to workers, and a behavior maintenance program was developed to encourage their continued use after training. These behavioral controls were introduced to appropriate workers in three different plants and were effective in changing all selected behaviors and conditions.

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We conducted a test of the usefulness of behavioral methods to control occupational health problems by reducing workers' exposures to toxic chemicals. Four plastics workers were trained in nine behaviors selected for potential to reduce their exposures to styrene, a common chemical with multiple toxic effects. Behavioral measures indicated that the workers quickly came to emit most of the behaviors.

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Thyroid function was evaluated in the Marshallese who were accidentally exposed to fallout-containing radioiodine isotopes in 1954. Measurements of thyrotrophin (TSH, thyroid-stimulating hormone) levels and free thyroxine (T4) index (FT4I) have revealed that, among 86 persons exposed on Rongelap and Ailingnae atolls, 14 have shown evidence of thyroid hypofunction. This was first noted in some individuals about ten years after exposure.

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Blood specimens from a sample of 373 Marshall Islanders were studied with reference to variants of 23 serum proteins and erythrocyte enzymes. Six of the traits studied exhibited genetic polymorphisms (adenosine deaminase, phosphoglucomutase1, acid phosphatase, 6-phosphogluconate dehydrogenase, haptoglobin, and group specific component). There were in addition four "rare" variants (albumin, transferrin, lactate dehydrogenase, and galactose-1-phosphate uridylyltransferase) involving nine persons, among 8,503 determinations.

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Cytogenetic studies of blood lymphocytes of Marshall Islanders, 10 years after their exposure to radiation from fallout in 1954, show chromosome-type aberrations in 23 of 43 exposed persons. Half the aberrations are of the exchange type. An unexpectedly large number of acentric fragments, but no exchange-type aberrations, appear in a few unexposed people on the same island.

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