Publications by authors named "Collette Owens"
Although methotrexate (MTX) is the most widely used therapy for central nervous system (CNS) prophylaxis in patients with diffuse large B-cell lymphoma (DLBCL), the optimal regimen remains unclear. We examined the efficacy of different prophylactic regimens in 585 patients with newly diagnosed DLBCL and high-risk for CNS relapse, treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) or R-CHOP-like regimens from 2001 to 2017, of whom 295 (50%) received prophylaxis. Intrathecal (IT) MTX was given to 253 (86%) and high-dose MTX (HD-MTX) to 42 (14%).
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- * Overall survival and disease-free survival rates after 10 years were both 77%; however, extranodal involvement was linked to worse outcomes compared to nodal involvement, indicating a hazard ratio of 3.44 for overall survival.
- * The study found that consolidating radiation therapy (RT) improved outcomes for patients with extranodal involvement, but this benefit diminished for those who were PET negative after treatment, with relapses primarily occurring
Background: Equality of care in pregnancy is important for all women, however can be difficult for healthcare providers to achieve. It has been found that culturally and linguistically diverse women born overseas generally have lower satisfaction with pregnancy care than women born in the host country.
Aim: Using a phenomenological framework, and models of care as a conceptual framework, this study explored the perceptions of care experienced by refugees and migrant women of culturally and linguistically diverse backgrounds who had participated in a community-based antenatal programme specialising in maternity care of multicultural women.