Publications by authors named "Colleen M Carey"
Biosimilars have the potential to greatly reduce US spending on biologic drugs, but uptake of these competitor products varies. We used Open Payments data from 2014 to 2022 to proxy for direct-to-physician marketing and compared levels of activity between biologic and biosimilar drug manufacturers. Our analysis focused on 6 reference biologics that recently faced competition in the years immediately before and after the launch of the first biosimilar.
View Article and Find Full Text PDFThe authors estimate the associations between community socioeconomic composition and changes in coronavirus disease 2019 (COVID-19) vaccination levels in eight large cities at three time points. In March, communities with high socioeconomic status (SES) had significantly higher vaccination rates than low-SES communities. Between March and April, low-SES communities had significantly lower changes in percentage vaccinated than high-SES communities.
View Article and Find Full Text PDFRollouts of COVID-19 vaccines in the USA were opportunities to redress disparities that surfaced during the pandemic. Initial eligibility criteria, however, neglected geographic, racial/ethnic, and socioeconomic considerations. Marginalized populations may have faced barriers to then-scarce vaccines, reinforcing disparities.
View Article and Find Full Text PDFArticle Synopsis
- Forty states require providers to check patients' prescription histories through state-run monitoring programs before prescribing controlled substances.
- A study in Kentucky found that PDMP queries for opioid prescriptions increased significantly from 12% to 56% after the implementation of a comprehensive PDMP mandate.
- While high-compliance providers began to reduce prescriptions for high-risk patients, low-compliance providers continued prescribing to these individuals, indicating that complete adherence to the mandate was still lacking.
Article Synopsis
- The paper examines the impact of a Kentucky policy that requires healthcare providers to check patients' opioid history before prescribing opioids.
- A comparison with Indiana, which did not implement such a policy, reveals significant changes in prescribing behavior, especially among low-volume providers.
- While some providers completely stopped prescribing opioids, the more notable change was prescribing to fewer patients, including those with simple or single-use needs.
Background: Providers are increasingly being expected to examine their patients' opioid treatment histories before writing new opioid prescriptions. However, little evidence exists on how patterns of potential opioid misuse are associated with subsequent adverse outcomes nationally.
Objective: To estimate how a range of patterns of potential opioid misuse relate to adverse outcomes during the subsequent year.