Publications by authors named "Colin J Adams"
Background: Approximately 50% of patients with interstitial lung disease (ILD) experience frailty, which remains unexplored in acute exacerbations of ILD (AE-ILD). A better understanding may help with prognostication and resource planning. We evaluated the association of frailty with clinical characteristics, physical function, hospital outcomes, and post-AE-ILD recovery.
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- A study highlighted the need for data on how different antifibrotic therapies affect patients with idiopathic pulmonary fibrosis (IPF), particularly for those whose lung function is declining.
- Researchers examined patients who experienced a significant decline in lung function while on antifibrotic treatment and found that continuing therapy was linked to less further decline and a lower risk of severe outcomes, compared to stopping the medication.
- The results emphasized that ongoing antifibrotic therapy helps reduce future lung function decline and lowers the probability of death or needing a lung transplant, even in real-world settings.
Background And Objective: Despite the high mortality of acute exacerbations of interstitial lung disease (AE-ILD), there is minimal evidence to guide management decisions. We aimed to assess the feasibility and outcomes of a standardized management protocol for AE-ILD.
Methods: We performed a retrospective cohort study of patients with AE-ILD admitted to hospital between January 2015 and August 2019.
Rationale And Objectives: In patients with severe emphysema and poor quality of life, bronchoscopic lung volume reduction (BLVR) may be considered and guided based on lobar emphysema severity. In particular, x-ray computed tomography (CT) emphysema measurements are used to identify the most diseased and the second-most diseased lobes as BLVR targets. Inhaled gas magnetic resonance imaging (MRI) also provides chronic obstructive pulmonary disease (COPD) biomarkers of lobar emphysema and ventilation abnormalities.
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