Publications by authors named "Colette Nickodem"

Article Synopsis
  • The study explores the prevalence of bacteria that cause gastroenteritis in Rhesus macaques, which can lead to post-infectious irritable bowel syndrome (PI-IBS).
  • It highlights that 21.6% of the bacterial isolates were resistant to quinolones, with significant findings showing that qPCR detected more positive cases than traditional culture methods.
  • The research emphasizes that gastrointestinal disease in Rhesus macaques is a critical issue in both health and welfare, contributing to high rates of hospitalization and euthanasia in these animals.
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Article Synopsis
  • Infection might trigger post-infectious irritable bowel syndrome (IBS) in humans and possibly cause a similar condition in rhesus macaques.
  • The study presents the complete genomes of 8 isolates and 103 isolates derived from rhesus macaques, examining both those with intestinal disease and those without.
  • Understanding these genetic isolates could help in exploring the link between infection and IBS, enhancing knowledge of gastrointestinal disorders.
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Post-harvest mitigation techniques are insufficient at addressing harbored in cattle lymph nodes, necessitating the exploration of pre-harvest alternatives that reduce prior to dissemination to the lymph nodes. A 2 × 2, unbalanced experiment was conducted to determine the effectiveness of pre-harvest treatments applied to the pen surface for mitigation in cattle. Treatments included manure slurry intended to mimic pen run-off water (n = 4 pens), a bacteriophage cocktail (n = 4), a combination of both treatments (n = 5), and a control group (n = 5) that received no treatment.

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Article Synopsis
  • Salmonella can linger in feedlot pens, spreading between cattle and contaminating the environment through feces.
  • A study over 7 months found a 57.7% prevalence of Salmonella in various samples, with the highest rates in the pen environment (76.0%) and feces (70.9%).
  • Different Salmonella serovars showed varied behaviors in their migration between the environment and cattle, indicating a need for tailored strategies to control specific serovars' spread to improve food safety.
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The use of antibiotics to treat dairy calves may result in multidrug-resistant extended-spectrum beta-lactamase (ESBL)-producing . This study investigated fluoroquinolone and macrolide resistance genes among ESBL-producing isolated from dairy calves. Fresh fecal samples from 147 dairy calves across three age groups were enriched to select for ESBL-producing Plasmid-mediated fluoroquinolone (), macrolide ((A)), and beta-lactam ( groups 1 and 9) resistance genes were identified by PCR and gel electrophoresis in ESBL-producing .

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Short-chain fatty acids (SCFAs) are by-products from microbial metabolism of fibers with anti-inflammatory effects. SCFAs may mitigate inflammatory conditions such as obesity through modulation of histone acetylation. Lipid metabolism and inflammation play critical roles during pregnancy.

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Problem: Recently characterized interferon epsilon (IFNe) protects against sexually transmitted infections, including genital herpes simplex virus (HSV), in animal models. There are no reports of IFNe in genital tract secretions of pregnant women, and data on IFNe in non-pregnant women are limited. This pilot study is the first to measure concentrations of IFNe in vaginal and cervical secretions during pregnancy and compare values between healthy and genital HSV-infected women.

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