Evaluation of Prospectively Followed Adult Patients with Erythema Migrans Using the Beck Depression Inventory Second Edition.

Background: The Beck Depression Inventory (BDI-II) may be used to evaluate individuals for symptoms of depression.

Methods: In a 1-year prospective study, 52 adult Lyme disease patients with erythema migrans and 104 matched control subjects were clinically assessed and completed the BDI-II at study entry and approximately 6 and 12 months later following antibiotic treatment.

Results: The mean BDI-II score was significantly higher at the baseline visit among Lyme disease patients compared with controls (P = .