[Inflammatory pseudotumour of the liver: case report and review of the literature].

We report a case of inflammatory pseudotumour of the liver in a 53-year-old woman who over the previous month had presented malaise, fever and right-sided hypochondralgia. On physical examination the liver was tender at palpation 2 cm below the right costal margin. Laboratory data were normal.

[Non-functioning neuroendocrine tumor of the pancreas: report of a clinical case and review of the literature].

The authors report the case of a 26-year-old woman, with a palpable abdominal mass, dyspepsia, pain and weight loss. These symptoms were caused by a non-functioning or biologically inactive neuroendocrine tumour (BINT), weighing 510 g and located in the tail of the pancreas. The treatment opted for was a surgical resection consisting in a distal pancreatectomy.

Effusion cytology of hepatocellular carcinoma.

Objective: To evaluate effusion cytology on routine smears in patients with hepatocellular carcinoma.

Study Design: Filed smears from 106 patients with autopsy-proven hepatocellular carcinoma were retrospectively reviewed for the presence of malignant cells. Morphologic patterns, as well as immunochemical reactivity for a panel of antibodies, were analyzed when feasible.

Cervical cytopathology. An evaluation of its accuracy based on cytohistologic comparison.

Background: Although Papanicolaou cytology represents the most effective technique to prevent and detect precancerous conditions of the uterine cervix, its false-negative yield is still a reason of concern among pathologists and gynecologists.

Methods: Because histologic control is one of the best ways to assess the accuracy of cytology diagnosis, the authors have investigated 1000 women who had cervical smears and tissue sampling obtained during the same colposcopic evaluation between 1987 and 1990.

Results: Out of 1000 cases (average age, 34.

The positive peritoneal effusion. A retrospective study of cytopathologic diagnoses with autopsy confirmation.

The distribution of 215 malignant tumors responsible for peritoneal effusions was investigated with respect to cytohistologic correlation and autopsy features. In males, cancer of the gastrointestinal tract, pancreas and liver were the most frequently observed forms, whereas in females tumors at gynecologic sites far outnumbered other neoplasms, such as stomach, bowel, pancreas, gallbladder and liver cancer. Cells from extra abdominal tumors, consistently seen in positive ascitic effusions, were from pleural mesothelioma and breast carcinoma, respectively, in males and females.

Cytopathology of malignant mesothelioma: a study of its patterns and histological bases.

We have reviewed the effusion cytology of 51 cases of histologically proven malignant mesothelioma of the pleura (49 cases) and the peritoneum (2 cases). The patient group included 45 males and 6 females, aged 45-83 yr. A cytological diagnosis of malignancy had been rendered on 43 cases, and in 30 of them it was consistent with, or at least suggestive of, a mesothelioma.

The positive pleural effusion. A retrospective study of cytopathologic diagnoses with autopsy confirmation.

We performed an investigation focusing on the distribution of tumor types responsible for positive pleural effusions in 143 patients who died of malignancy and underwent autopsy. The principal malignant tumors were lung carcinoma (41 cases, 51.2%) and pleural mesothelioma (23 cases, 28.

Cytological typing of primary lung cancer: study of 100 cases with autopsy confirmation.

In order to assess the accuracy of bronchial aspiration cytology in typing lung cancer, tissue sections from 100 autopsy cases of lung cancer were compared with the cytology features observed in the same patients prior to death. There was 100% accuracy in the cytology of small-cell carcinoma; 90% in squamous-cell carcinoma; 70% in adenocarcinoma; and 50% in undifferentiated large-cell carcinoma. The observed discrepancies probably reflect intrinsic tumor properties rather than problems attributable to either the bronchial aspiration method or cytology interpretation, especially in cases involving advanced lung carcinoma.

[Cervical cytologic screening in the province of Trieste].

The frequency of the Pap test and the incidence of dysplastic and neoplastic lesions of the uterine cervix in the province of Trieste from 1/7/85 to 30/6/88 have been analysed. Over this period, the annual frequency of screening was 11% of the resident female population, with considerable differences from one age class to another. In the age group between 15 and 29, in which CIN 1 incidence is at its maximum, the frequency of screening is much lower than it is among subjects of average age.

Cervical intraepithelial neoplasia with conization: early complications and follow-up.

The authors made a review of the last 100 cases who underwent a conization of the cervix during the period 1980-1986. Cyto-histological evaluation was compatible in 78% of the cases with a cervical intraepithelial neoplasia of third degree and in 22% with a CIN of first and second degree. Early post-operative complications consisted of a hemorrhage in 3% of the cases, easily stopped with a vaginal packing.

Recurrence incidence in follow-up of patients affected by condylomatosis of the uterine cervix with VCE (viral cytopathic effect).

The frequent association of HPV lesions with cytological and/or hystological alterations of CIN in the uterine portio and in the lower genital tract suggests their possible role in the genesis of precancerous lesions of the cervix. In the systematic cytological screening, condylomatous lesions present an incidence varying from 0.52% to 1.

Glycosaminoglycans and endochondral calcification.

Present controversy about endochondral calcification and ossification is concerned with changes in glycosaminoglycans. Some authors report a rise in amounts of glycosaminoglycans while others a fall. Cartilage was carefully sliced under microscopic control to provide samples of material from different functional zones of the developing tissues.