Effects of Procedural Information, Buzzy, and Multiple Interventions on Pain in Children Undergoing Venipuncture: A Randomized Controlled Trial.

Background: Needle-related procedures are commonly performed in childhood and lead to considerable pain.

Purpose: This randomized controlled study was conducted to compare the effects on venipuncture pain of the Buzzy, an informational animated video, multiple interventions, and standard care in children aged 6-12 years.

Methods: One hundred eighty children were assigned to the groups using a computerized randomization program.

'My Journey': A Qualitative Study of Recovery From the Perspective of Individuals With Chronic Mental Illness.

Due to the humanistic paradigm shift in recent years, mental health recovery has been approached through personal recovery beyond the limits of the biomedical perspective, emphasising the subjective perception and uniqueness of the individual. Therefore, approaching recovery perceptions from patients' perspectives has gained importance. This study aimed to examine in depth the recovery perceptions of individuals with chronic mental illness.

Assessment of physicians' knowledge, thoughts, and attitudes regarding the phytovigilance system.

Background: In this study, physicians' awareness of phytovigilance and their knowledge of safety processes for herbal products were evaluated for the first time in Türkiye.

Research Design And Methods: A descriptive quantitative study was conducted using face-to-face interview techniques with physicians working in a training and research hospital in Türkiye. A total of 268 (35.

Dietary and serum antioxidant capacity is inversely associated with patients in osteoarthritis: a case-control study.

This study aimed to examine dietary antioxidant and serum antioxidant capacity in patients with knee osteoarthritis (OA). This case-control study consisted of 47 patients with OA (case group) and 30 healthy subjects (control group). The control and case group were matched age, gender, and body mass index (p > 0.

Implantable, 3D-Printed Alginate Scaffolds with Bismuth Sulfide Nanoparticles for the Treatment of Local Breast Cancer via Enhanced Radiotherapy.

Surgical removal of tumor tissue remains the primary clinical approach for addressing breast cancer; however, complete tumor excision is challenging, and the remaining tumor cells can lead to tumor recurrence and metastasis over time, which substantially deteriorates the life quality of the patients. With the aim to improve local cancer radiotherapy, this work reports the fabrication of alginate (Alg) scaffolds containing bovine serum albumin (BSA)-coated bismuth sulfide (BiS@BSA) nanoradiosensitizers using three-dimensional (3D) printing. Under single-dose X-ray irradiation in vitro, Alg-BiS@BSA scaffolds significantly increase the formation of reactive oxygen species, enhance the inhibition of breast cancer cells, and suppress their colony formation capacity.

The association of fear of COVID-19 on occupational stress in pediatric nurses: Examining the mediating role of psychological well-being.

Purpose: This study investigated the associations of fear of COVID-19 with occupational stress and the mediating role of psychological well-being in pediatric nurses.

Methods: This cross-sectional study was conducted between December 2021 and February 2022. The sample consisted of 464 pediatric nurses from public or university hospitals in Türkiye.

Bacterial production of ciprofloxacin and potential usage as a radiotracer.

Infectious diseases caused by bacteria that have become resistant to antibiotics have increased in prevalence, necessitating new methods for their diagnosis and treatment. The aim of this study was to compare the efficacy of synthetic ciprofloxacin to that of organic ciprofloxacin produced by cave microorganisms, as well as to evaluate the feasibility of using organic ciprofloxacin radiolabeled with technetium-99m as an imaging agent. Organic ciprofloxacin produced by cave bacteria isolated from sediment taken from the dark zone of Antalya's "Yark Sinkhole," (Turkey's 14th deepest cave), was purified using high-performance liquid chromatography.

Oxygen transmission rates of skin substitutes and graft survival.

Aim: Oxygen is required for cell migration into the scaffold and for the survival of the overlying graft in the use of a single-layer scaffold. In the absence of diffusion from the avascular wound base, such as in areas above the bone/tendon, oxygen delivery from the lateral edges of the scaffold is important. This study compared the oxygen permeability of skin scaffolds, currently commercially available in Turkey (Nevelia®, MatriDerm®, and Pelnac®), in the lateral plane.

The effects of Capparis ovata seed oil on the healing of traumatic skin wounds.

Background: Capparis ovata contains alkaloids, lipids, polyphenols, flavonoids, and also is rich in antioxidants. Conventionally, in Turkey, the flower buds, root, bark, and fruits of C. ovata are used for their analgesic, anti-inflammatory, anti-rheumatism, tonic, and diuretic effects.

Artichoke for biochemistry, histology, and gene expression in obstructive jaundice.

Objective: This study aimed to evaluate the hepatoprotective effect of artichoke leaf extract (Cynara scolymus) in experimental obstructive jaundice.

Methods: Rats were separated into three groups, namely, sham, control, and artichoke leaf extract. Ischemia was created for 60 min, and then liver tissue and blood samples were taken at the 90th minute of reperfusion.

Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury.

Objective: The aim of this study was to evaluate the hepatoprotective effect and mechanism of action of artichoke leaf extract in hepatic ischemia/reperfusion injury.

Methods: Rats were divided into three groups such as sham, control, and artichoke leaf extract groups. Antioxidant enzyme activities and biochemical parameters were examined from the tissue and serum obtained from the subjects.

Can Intralesional Epidermal Growth Factor Reduce Skin Graft Applications in Patients with Diabetic Foot Ulcer?

Background: Diabetic foot ulcer (DFU) is a serious health problem. Major amputation increases the risk of mortality in patients with DFU; therefore, treatment methods other than major amputation come to the fore for these patients. Graft applications create an appropriate environment for the reproduction of epithelial cells.

The role of vulpinic acid as a natural compound in the regulation of breast cancer-associated miRNAs.

Background: Breast cancer is the most frequently diagnosed cancer, and no effective treatment solution has yet been found. The number of studies based on the research of novel natural compounds in the treatment of breast cancer has been increasing in recent years. The anticancer properties of natural compounds are related to the regulation of microRNA (miRNA) expression.

Vulpinic acid as a natural compound inhibits the proliferation of metastatic prostate cancer cells by inducing apoptosis.

Background: Lichen secondary metabolites have drawn considerable attention in recent years due to the limitations of current treatment options. Vulpinic acid (VA) obtained from Letharia vulpina lichen species exerts a remarkable cytotoxic effect on different cancer types. However, the therapeutic efficacy of VA in metastatic prostate cancer (mPC) cells has not been investigated.

The Mid-Term Effects of Transit Bipartition with Sleeve Gastrectomy on Glycemic Control, Weight Loss, and Nutritional Status in Patients with Type 2 Diabetes Mellitus: a Retrospective Analysis of a 3-Year Follow-up.

Background: Metabolic surgery is an effective treatment method for glycemic control and weight loss in obese patients with type 2 diabetes mellitus (T2DM). This study aimed to present the mid-term metabolic effects and weight loss results of the patients with T2DM who underwent transit bipartition with sleeve gastrectomy (TB-SG).

Methods: A total of 32 obese patients with T2DM who underwent TB-SG were included in the study.

An Overview of Deep Learning Algorithms and Their Applications in Neuropsychiatry.

Deep learning (DL) algorithms have achieved important successes in data analysis tasks, thanks to their capability of revealing complex patterns in data. With the advance of new sensors, data storage, and processing hardware, DL algorithms start dominating various fields including neuropsychiatry. There are many types of DL algorithms for different data types from survey data to functional magnetic resonance imaging scans.

Mitigating medical student stress and anxiety: Should schools mandate participation in wellness intervention programs?

Purpose: Medical students are at increased risk of poor mental health and need to regularly engage in preventive programs to maintain well-being. However, many do not and it remains an open question whether these programs should be mandatory. We implemented a RCT to examine the effectiveness of assigning medical students to a wellness intervention on adherence to engagement in the assigned intervention and on psychological and academic outcomes.

Latent profile analysis of COVID-19 fear, depression, anxiety, stress, mindfulness, and resilience.

The purpose of the current study was to identify latent profiles of COVID-19 fear, depression, anxiety, stress, mindfulness, and resilience among university students. A total of 506 university undergraduate and graduate students from various universities were recruited through online platforms in Turkey. Data were collected utilizing self-report scales and were analyzed utilizing latent profile analysis.

Impaired auditory and visual time reproduction in adult patients with attention deficit-hyperactivity disorder.

Although impaired time perception is associated with significant disturbance in the everyday functioning of adult patients with Attention Deficit-Hyperactivity Disorder (ADHD), it is not very well studied. The present study aimed to evaluate both visual and auditory time reproduction (TR) by using eight time intervals in adult ADHD patients compared to healthy controls (HC). Wechsler Adult Intelligence Scale-R (WAIS-R), Adult Attention Deficit-Hyperactivity Disorder Self-Report Scale (ASRS), Wender Utah Rating Scale (WURS), Hyperfocusing Scale (HS), Beck Depression Inventory (BDI) and a 2-back task were administered to participants.

Live Donor Assessment Tool (LDAT): A Turkish validity and reliability study.

Background/aims: Psychosocial and psychiatric evaluations are crucial components of the assessment of a live donor candidate. The Live Donor Assessment Tool (LDAT) was developed for this purpose. This study aims to evaluate the validity and reliability of the Turkish version of LDAT.

Human and animal cystic echinococcosis in Konya, Turkey: molecular identification and the first report of E. equinus from human host in Turkey.

Cystic echinococcosis is a neglected, zoonotic disease in Turkey. The disease is commonly seen in rural areas where the local population is in close contact with livestock and dogs. This research aimed to molecularly identify of hydatid cysts in cattle and human isolates from Konya, Turkey.

Assessment of nurses' respect for patient privacy by patients and nurses: A comparative study.

Aims: To determine whether nurses respect or violate patient privacy by comparing nurses' and patients' opinions.

Background: Although nurses want to respect patient privacy, they can sometimes violate patient privacy or not pay enough attention.

Method: This comparative and cross-sectional study was conducted with 357 patients and 305 nurses in 12 public hospitals in Trabzon, Turkey.