Publications by authors named "Colagrande C"

Purpose: To assess whether secretin stimulation improves visualization of the pancreatic ducts at magnetic resonance (MR) cholangiopancreatography (MRCP) in patients with severe chronic pancreatitis or suspected pancreatic disease.

Materials And Methods: Thirty-one patients (group 1) with chronic pancreatitis and 84 patients (group 2) with clinical and/or laboratory findings suggestive of pancreatic disease who did not have ductal alterations at ultrasonography (US) and/or computed tomography (CT) underwent MRCP before and up to 10 minutes after secretin stimulation. Size of the main pancreatic duct (head, body, tail) and duodenal filling before and after secretin stimulation were measured quantitatively.

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Aim Of The Study: Magnetic Resonance pancreatography (MRP) was performed before and after the intravenous injection of secretin to assess the improvement in pancreatic duct visualization and to perform a dynamic study of the pancreatic exocrine function.

Material And Methods: 20 MRP examinations were performed in 18 patients with suspected or known chronic pancreatitis. Coronal T2-weighted half-Fourier SSFSE images were obtained with a phased array surface coil.

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Considering the several suggestions regarding the future developments of echocontrast agents, there is a striking difference between the few compounds actually available on the market and used in clinical practice and those undergoing experimental clinical trials. It is therefore difficult to predict what will be the actual impact of these agents in the next future. Future developments will probably go beyond color enhancement which was the end-point till a very short time ago.

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This study was aimed at evaluating the capabilities of Doppler US in the quantitative study of portal blood flow after glucagon administration in normal subjects. While its role in the qualitative study of portal hemodynamics is well known, it remains questionable whether Doppler US may be a valuable tool for the quantitative study of portal blood velocity. This may be solved by introducing, on a routine basis, meal tests which may provide a relative evaluation of the data.

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Twenty-one patients with clinically suspected recurrence of ovarian (n = 3) or uterine (n = 18) carcinoma were examined with suprapubic ultrasound (US) and transrectal US with high-frequency linear probes. The examinations were performed 3, 6, 9, and 15 months after surgery and radiation therapy. Eight patients underwent radiation therapy before surgery and ten after surgery; three underwent only surgery.

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Endoscopic retrograde biliary drainage by means of transtumoral endoprostheses is an effective technique for palliative decompression of malignant biliary obstruction. However, serial follow-up is required for an early detection of eventual long-term complications. In the present study 37 patients with malignant biliary obstruction, treated by endoscopic insertion of one or more biliary stents, were prospectively evaluated by sonography, with serial clinical and US examinations up to 10 months.

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Fourteen cases of hemobilia of traumatic (six), vascular (six) or neoplastic (two) origin were reviewed. Eleven patients obtained correct diagnosis only be integration of at least two diagnostic procedures out of Ultrasonography, Computed Tomography, arteriography and cholangiography. Although US and CT are extremely useful as screening procedures, correct diagnosis should be only possible by integration of more diagnostic technics.

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57 patients affected by liver metastases were examined with different types of dynamic ultrasound scanners (linear-sector-convex) in order to assess the advantages and the limits of each scanner and to evaluate if a better diagnostic accuracy is possible by using 2 types of scanner in the same patient. The results were estimated at 3 different levels: quantitative analysis where we considered only the presence or not of liver metastases; complex quantitative analysis where we also evaluate number and site of the metastases; qualitative structural analysis where we compared the ultrasonographic appearance of the metastases. All the results were evaluated by a personal computer with a special program and a statistical analysis was elaborated.

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120 patients with clinical suspected prostatic neoplasm were evaluate by transrectal linear sonography. 26 normal glands, 57 hypertrophic adenomas and 37 adenocarcinomas were recognized. We had 17 false positive cases for adenocarcinoma in hypertrophic adenomas.

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The sonographic findings in eight cases of splenic infarct at their onset and at different phases of their development have been retrospectively analyzed. A wide range of appearances was seen (single or multiple, rounded or wedge-shaped, echo-free, hypoechoic, and hyperechoic lesions). In our opinion, such variable appearances are related to the age of the infarct (hypoechoic or echo-free in the earlier stages, hyperechoic in healed infarcts).

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Ultrasound was used for a serial evaluation of gallbladder modifications in 61 patients with acute viral hepatitis during both the acute phase of the illness and recovery. Most of the patients studied within 7 days from the onset of symptoms and/or jaundice showed sonographic abnormalities of the gallbladder (increased wall thickness, reduced volume, abnormal bile content). A normal ultrasound pattern of the gallbladder was progressively restored during the clinical recovery in most of the patients.

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Five hundred and two patients with good opacification of the gallbladder were studied by means of ceruletide-assisted cholecystography. A high percentage (15.7; 79 patients) was found to have hyperplastic cholecystoses.

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Results of US study in 30 children with various renal lesions are reported, and compared with clinical and surgical features. Different ultrasonographic aspects are discussed with special interest on cogenital abnormalities. US is proposed as first choice investigation in newborns with antenatal ultrasonographic demonstration of renal lesions and in all patients where a mass of renal origin is suspected.

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In 511 patients with clinical symptoms of chronic or acute biliary disease, gallbladder area was studied by automatic equipments. In 39 patients different features of the gallbladder wall lesions were demonstrated, in some cases associated with gall stones or bile modifications. Gallbladder wall lesions were divided in three different groups, diffuse, localized or both, according to their appearance and extension.

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Cholecystography has been up to day used as unique or first instance examination in patients suspected to have chronic gallbladder diseases. On the other hand, cholecystosonography is proposed with increasing frequence as first examination for simple and rapid detection of cholelithiasis. Results of high standard cholecystography are therefore welcomed in order to assess it present role in respect to diagnostic ultrasounds.

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A case of bilateral pheochromocytoma presenting as primarily cystic suprarenal masses is reported. The computed tomographic manifestations, possible etiology, and differential diagnosis of these cystic suprarenal lesions are discussed.

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In 12 X-ray and gastroenterology departments 1570 patients, clinically suspected to have a gastric pathology, have been examined by double contrast (surface) examination of the stomach followed by gastroscopy. Diagnostic accuracy was 93% in respect of endoscopic data, assumed correct by hypothesis. On the basis of a cost and benefit evaluation, made according to the well known criteria, a wider routine use of the double contrast technique is proposed.

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