The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion.

Life histories of oviparous species dictate high metabolic investment in the process of gonadal development leading to ovulation. In vertebrates, these two distinct processes are controlled by the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH), respectively. While it was suggested that a common secretagogue, gonadotropin-releasing hormone (GnRH), oversees both functions, the generation of loss-of-function fish challenged this view.

The Thermal Signature of Wound Healing.

Background: Despite major efforts in prevention, surgical site infections (SSIs) remain a burden on patients and the healthcare system and are associated with significant morbidity. SSIs are one of the costliest healthcare-associated infections. The diagnosis of SSIs is based mainly on clinical assessment, which may result in a delay in detection.

New Bone Growth into Surgical Bone Defects Grafted with a Novel Cultivated Coral Graft: A Histomorphometric Study in Rabbit Calvarias.

Natural Coral Particles (NCPs) are a suitable scaffold material for Guided Bone Regeneration (GBR) procedures; it combines the placement of a bone substitute supporting a barrier membrane. Due to increasing sea pollution and the declarations of endangered coral species (KYOTO 1997), they are no longer suitable for the medical industry. Novel domestic corals have been grown under controlled conditions to produce cultivated coral graft (CCG) material.

New Bone Growth into Surgical Bone Defects Grafted with a Novel Cultivated Coral Graft: A Histomorphometric Study in Rabbit Calvarias.

Purpose: To evaluate a new cultivated coral graft (CCG) in an in vivo experimental guided bone regeneration (GBR) procedure.

Materials And Methods: The calvarias of eight rabbits were surgically exposed, and circular defects 8 mm in diameter were prepared. One defect was filled with CCG particles (experimental group); the contralateral defect (control group) was spontaneously filled by blood clot.

Thermal Changes of One-Piece Versus Two-Piece Implants During Setting of an Autopolymerized Acrylic Resin.

To evaluate differences in the temperature rise at the cervical area of one-piece vs two-piece implants during the setting of relined provisional crowns. A K-type thermocouple was fixed to the coronal thread of 15 one-piece implants and 15 two-piece implants that were mounted on a plexiglass apparatus. Baseline temperature (Bl Temp) was recorded before starting the curing process.

Immediate Maxillary Full-Arch Rehabilitation of Periodontal Patients with Terminal Dentition Using Tilted Implants and Bone Augmentation: A 5-Year Retrospective Cohort Study.

Background: All-on-four protocols with tilted implants in the maxilla are used to rehabilitate the terminal dentition of the severe generalized periodontitis patients. Data on long-term biological complications are scarce.

Methods: Eighty-four axial and forty-six tilted immediate implants have been placed in the extraction sockets of 23 patients according to a four-six implants protocol combined with ridge augmentation.

Histologic and Histomorphometric Evaluation of a Connective Tissue Graft Retrieved with a Novel Deepithelialization Procedure: A Case Series.

Various free connective tissue graft (CTG) harvesting techniques have been reported. The lining epithelium of the palatal graft may be retrieved either intra- or extraorally. This report presents a series of root coverage cases where deepithelialization was intraorally performed before harvesting the graft with a round diamond bur mounted on a low-speed handpiece.

Coronally Advanced Flap with Connective Tissue Graft for Treating Orthodontic-Associated Miller Class III Gingival Recession of the Lower Incisors: A One-Year Retrospective Study.

(1) Background: To assess the clinical outcome of coronally advanced flap combined with connective tissue graft for the treatment of orthodontic-associated Miller Class III gingival recession of the lower incisors. (2) Methods: This study included 15 patients who had undergone orthodontic treatment prior to development of recession. Measurements of recession depth, recession width, probing depth, and width of keratinized tissue were performed clinically immediately before surgery and after one year.

The Effect of Coronal Implant Design and Drilling Protocol on Bone-to-Implant Contact: A 3-Month Study in the Minipig Calvarium.

Stress concentrated at an implant's neck may affect bone-to-implant contact (BIC). The objective of this study was to evaluate four different implant neck designs using two different drilling protocols on the BIC. Ninety-six implants were inserted in 12 minipigs calvarium.

Thermal Changes at the One-Piece Implant Surface During the Setting of Two Autopolymerized Acrylic Resins.

Purpose: To compare the temperature changes during the setting process of two provisional crown materials, polymethyl methacrylate (PMMA)-based acrylic resin (Ac) and bis-acryl composite resin (Co), at the first thread surface of one-piece implants.

Materials And Methods: Twenty-two 3.3-mm-diameter one-piece implants were divided into two groups according to the provisional restoration material.

Supportive periodontal therapy affects dental implants probing pocket depth, bleeding on probing, and bone level: a 4- to 8-year follow-up study.

Objective: To evaluate implant and patient characteristics 4 to 8 years after implant installation in a study involving immediate fixed restoration of dental implants. Method and materials: The study was a follow-up of treated generalized chronic periodontitis patients who received immediate restorations on dental implants as part of a previous study. The patients were examined clinically and radiographically at implant placement, 6 months, 1 year, and 4 to 8 years later.

Oral and dental considerations of combat-induced PTSD: a descriptive study.

Objective: Stress experienced as an intense and traumatic event can increase the odds of orofacial morbidities that may affect oral, periodontal, or masticatory system health. The aim of this study was to evaluate the dental, periodontal, oral, and bruxism situation among Israeli posttraumatic stress disorder (PTSD) war veterans.

Method And Materials: This retrospective cohort pilot study aimed to examine the oral and facial manifestations in 71 Israeli veterans with combat PTSD.

Does cognitive flexibility affect the course of labor? A prospective study.

Objective: To evaluate cognitive flexibility and labor and delivery outcomes.

Methods: A prospective study was conducted of nulliparas with singleton term pregnancy, admitted for labor to a tertiary referral center from 1 January to 31 July, 2017. After epidural anesthesia, parturients completed the validated Psychological Flexibility Questionnaire (20 questions that evaluate a person's level of cognitive flexibility) before delivery.

Can we predict the need for antihypertensive treatment during the early postpartum period for women with preeclampsia or gestational hypertension?

Objectives: To determine factors that predict the need for antihypertensive treatment during early postpartum period among women with preeclampsia or gestational hypertension.

Study Design: Retrospective cohort of 358 women.

Main Outcome Measures: Demographic, clinical and laboratory data of 63 women diagnosed with preeclampsia or gestational hypertension during a singleton pregnancy and who needed antihypertensive agents during early postpartum period were compared to 295 who did not.

Postcoital bleeding is a predictor for cervical dysplasia.

Background: Postcoital bleeding (PCB) is a common gynecological symptom that may cause concern among both patients and physicians. Current literature is inconclusive regarding management recommendations.

Objective: To identify risk-factors for dysplasia/cancer among patients presenting post-coital bleeding (PCB).

Clinical and Patient-Related Outcomes of a Tapered Implant System With Switched Platform Conical Abutments: A Private Practice Field Trial.

The aim of this prospective cohort observational field trial was to examine 1-year survival and success rates of a recently introduced tapered implant system with switched platform conical abutments and to evaluate patient related outcomes of therapy. Partially edentulous patients aged between 18 and 75 years, with available bone height for dental implants ≥10 mm desiring to restore the missing tooth/teeth with implant supported restoration, were recruited by 7 periodontists in their respective private practices. Dental implants were installed according to standard implant therapy protocol.

Comparison between mineralized cancellous bone allograft and an alloplast material for sinus augmentation: A split mouth histomorphometric study.

Background: Several grafting materials have been used in sinus augmentation procedures including autogenous bone, demineralized freeze-dried bone, hydroxyapatite, β-tricalcium phosphate, anorganic deproteinized bovine bone, and combination of these and others. Yet, the issue of the optimal graft material for sinus floor augmentation is controversial.

Purpose: This prospective, randomized split-mouth study was undertaken to histomorphometrically compare a biphasic calcium phosphate (BCP) alloplastic bone substitute and a human bone mineral allograft (freeze-dried bone allograft, FDBA) in patients undergoing bilateral maxillary lateral sinus floor augmentation.

Differences in crestal bone-to-implant contact following an under-drilling compared to an over-drilling protocol. A study in the rabbit tibia.

Objectives: The objective of this study is to compare bone-to-implant contact (BIC) between implants inserted at high torque due to under-drilling of the crestal bone to those inserted at low torque due to over-drilling of the crestal bone.

Materials And Methods: Forty implants with diameters of 3.75 mm (group A) or 3.

Primary stability following abutment preparation of one-piece dental implants.

Purpose: One-piece dental implants are commonly used for the immediate restoration of missing teeth. In most cases, the clinician has to prepare the abutment intraorally to ensure a proper emergence profile and abutment angulation. However, this procedure might impair primary stability and thus potentially compromise osseointegration.

A novel device for resonance frequency assessment of one-piece implants.

Purpose: Immediate loading and/or restoration of dental implants requires the assessment of implant stability, which is best performed by resonance frequency analysis (RFA) prior to loading. One-piece dental implants are usually used for immediate loading, but there is currently no available reliable method to assess the primary stability of one-piece dental implants. Therefore, this study sought to validate a novel device designed for RFA measurements of one-piece implants.

Heat production during prosthetic preparation of a one-piece dental implant.

Purpose: Preparation of a one-piece dental implant abutment is often needed to achieve a proper emergence profile for a definitive restoration. However, this procedure may compromise osseointegration through the production of heat. The aim of this study was to measure heat production during implant abutment preparation with different volumes of water irrigation using a one-piece implant system.

Cooling profile following prosthetic preparation of 1-piece dental implants.

The aim of this study was to evaluate the effect of water irrigation on heat dissipation kinetics following abutment preparation of 1-piece dental implants. UNO 1-piece dental implants were mounted on Plexiglas apparatus clamping the implant at the collar. T-type thermocouple was attached to the first thread of the implant and recorded thermal changes at 100 millisecond intervals.

Physiological and molecular evidence of heat acclimation memory: a lesson from thermal responses and ischemic cross-tolerance in the heart.

Sporadic findings in humans suggest that reinduction of heat acclimation (AC) after its loss occurs markedly faster than that during the initial AC session. Animal studies substantiated that the underlying acclimatory processes are molecular. Here we test the hypothesis that faster reinduction of AC (ReAC) implicates "molecular memory.

Altered Ca2+ handling and myofilament desensitization underlie cardiomyocyte performance in normothermic and hyperthermic heat-acclimated rat hearts.

Heat acclimation (AC) improves cardiac mechanical and metabolic performance. Using cardiomyocytes and isolated hearts from 30-day and 2-day acclimated rats (AC and AC-2d, 34 degrees C), we characterized cellular contractile mechanisms under normothermic (37 degrees C) and hyperthermic (39-42 degrees C) conditions. To determine contractile responses, Ca2+ transients (Ca2+ T), sarcoplasmic reticulum (SR) Ca2+ pool size (fura-2/indo-1 fluorescence), force generation [amplitude systolic motion (ASM)], L-type Ca2+ channels [dihydropyridine receptor (DHPR)], ryanodine receptors (RyRs), and total (PLBt) and phosphorylated phospholamban [serine phosphorylated (PLBs) and theonine phosphorylated (PLBtr)] proteins and transcripts were measured (Western blot, RT-PCR).