The study aimed to investigate the prevalence of Pediatric Post-COVID-19 Condition (PPCC), identify associated risk factors, and evaluate the quality of life in children based on the severity of their acute COVID-19 illness.
A total of 579 children participated, with 260 experiencing mild COVID-19, 60 with severe disease, and 259 as a control group; results indicated that those with severe COVID-19 had a significantly higher prevalence of PPCC compared to mild cases and controls.
Findings showed that while prevalence of PPCC decreased over time, children exhibiting PPCC had worse physical health-related quality of life and fatigue, with risk factors including prior health issues, hospitalizations, and ongoing fatigue one month post-infection.
Pediatric post coronavirus disease 2019 (COVID-19) condition (PPCC) is a complex syndrome affecting children's daily lives, and this study aimed to uncover specific phenotypes to improve understanding and treatment.
Researchers analyzed data from 111 children aged 3-18 with diagnosed PPCC, identifying three distinct clusters based on symptoms and demographics.
The study found variations in age, sex, symptom patterns, and daily life impact among the clusters, emphasizing the need for further research into the diverse causes of post-COVID symptoms in children.
Background: Long-COVID is a well-documented multisystem disease in adults. Far less is known about long-term sequelae of COVID in children. Here, we report on the occurrence of long-COVID in Dutch children.