Publications by authors named "Cody Parsons"

Background: Bleeding during cardiac surgery may be refractory to standard interventions. Off-label use of factor eight inhibitor bypass activity (FEIBA) has been described to treat such bleeding. However, reports of safety, particularly thromboembolic outcomes, show mixed results, and reported cohorts have been small.

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Article Synopsis
  • Cardiovascular disease is the leading cause of death for women, yet many drug trials fail to adequately assess how treatments affect women specifically, despite evidence of sex differences in responses to medications.
  • The FDA has made efforts since 1993 to get more women involved in clinical trials, but progress in representation and reporting sex-specific data in studies remains slow.
  • This review highlights the need for more sex-specific analysis in cardiovascular drug therapies and shows that while some areas like antihypertensives have better female representation, others like heart failure therapies need improvement.
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