Publications by authors named "Cody Andreoni"
J Trauma Acute Care Surg
April 2020
Article Synopsis
- Rats that got brain cell transplants were studied to see how the location of the transplant affected their recovery after a brain injury.
- The study found that putting the cells around the injury helped save more brain tissue and improved movement better than putting them directly in the injury.
- This suggests that where you place neural stem cells can really matter when trying to heal brain injuries.
Article Synopsis
- Penetrating traumatic brain injury (PTBI) significantly contributes to death and disability in the U.S., and inflammasomes play a crucial role in the inflammatory response mediated by interleukin-1β following such injuries.
- In a study involving male Sprague-Dawley rats, researchers examined the expression of inflammasome components and related proteins after brain injury, finding peaks in certain protein expressions at 48 hours post-injury.
- The research identified specific cell types, particularly activated microglia, that exhibited sustained inflammasome activation, indicating a prolonged inflammatory state conducive to potential therapeutic interventions for PTBI.
