Effect of a specially formulated diet on progression of heart enlargement in dogs with subclinical degenerative mitral valve disease.

Background: Previous studies in dogs with degenerative mitral valve disease (DMVD) have identified altered myocardial energy metabolism and oxidation, which might contribute to cardiac hypertrophy. Diets rich in medium chain fatty acids and antioxidants are a potential means of treatment. A previous clinical study found significantly smaller left atrial diameter (LAD) and left atrium-to-aorta diameter ratio (LA : Ao) in dogs with subclinical DMVD fed a specially formulated diet vs control diet for 6 months.

Arrhythmogenic right ventricular cardiomyopathy in Bulldogs: Evaluation of clinical and histopathologic features, progression, and outcome in 71 dogs (2004-2016).

Objectives: This study aimed to characterize the clinical and histopathological features of arrhythmogenic right ventricular cardiomyopathy (ARVC) in English Bulldogs, American Bulldogs, and Bulldog-type mixed breed dogs and assess affected Bulldogs for a striatin gene mutation previously reported in Boxers with ARVC.

Animals: Seventy-one Bulldogs fit the inclusion criteria. Genetic analysis was performed on five dogs.

Transatrial stenting for long-term management of cardiac tumor obstruction of the right atrium in 3 dogs.

Background: Venous obstruction in dogs caused by large intracardiac masses can result in severe morbidity with few safe treatments.

Hypothesis/objectives: Retrospective study to report results after transatrial stent placement in dogs with naturally occurring cardiac masses causing venous obstruction.

Animals: Three client-owned dogs diagnosed with large cardiac masses.

Pharmacodynamic effects of ivabradine, a negative chronotropic agent, in healthy cats.

Objective: To determine the pharmacodynamic effects of oral ivabradine in cats.

Animals: Eight healthy, adult domestic short hair cats.

Methods: Each cat underwent four study periods of 24 h, receiving either one dose of placebo or ivabradine (0.

White-coat effect on systemic blood pressure in retired racing Greyhounds.

Background: Greyhounds are known to have a higher systemic arterial blood pressure (BP) than non-Greyhound dogs.

Objectives: The purpose of this study was to determine whether the high systemic BP was because of the white-coat effect.

Animals: Twenty-two healthy retired racing Greyhounds (RRG) enrolled in a blood donation program.

Proactive personality and the successful job search: a field investigation with college graduates.

The current article tests a model of proactive personality and job search success with a sample of 180 graduating college students. Using structural equation modeling, the authors tested a theoretical model that specified the relations among proactive personality, job search self-efficacy, job search behaviors, job search effort, and job search outcomes. Job seekers were surveyed at 2 separate points in time, once 3-4 months prior to graduation and once 2-3 months following graduation.

Hypothermia-enhanced splenic cytokine gene expression is independent of the sympathetic nervous system.

Splenic nerve denervation abrogates enhanced splenic cytokine gene expression responses to acute heating, demonstrating that hyperthermia-induced activation of splenic sympathetic nerve discharge (SND) increases splenic cytokine gene expression. Hypothermia alters SND responses; however, the role of the sympathetic nervous system in mediating splenic cytokine gene expression responses to hypothermia is not known. The purpose of the present study was to determine the effect of hypothermia on the relationship between the sympathetic nervous system and splenic cytokine gene expression in anesthetized F344 rats.