Hypofractionated Stereotactic Radiation Therapy for Metastatic Adenocarcinoma ex Goblet Cell Carcinoid of the Appendix: Case Report and Literature Review.

Adenocarcinoma ex-goblet carcinoid (ADA ex-GCC) is a rare and aggressive subtype of goblet cell carcinoid, a distinct tumor of the appendix characterized by both neuroendocrine and glandular differentiation. Patients often present with chronic abdominal pain or symptoms of acute appendicitis. Right hemicolectomy is the primary mode of treatment, and prophylactic salpingo-oophorectomy and hysterectomy is recommended in post-menopausal women due to the tumor's propensity of transcoelemic spread, especially to the ovaries.

Dropout rates in exposure with response prevention for obsessive-compulsive disorder: What do the data really say?

The purposes of this review were to: 1) determine the attrition rates for exposure with response prevention (ERP) for obsessive-compulsive disorder (OCD), 2) compare them to those in other treatments for OCD, and 3) identify predictors of ERP attrition. A systematic literature search of randomized controlled trials for ERP for OCD yielded 21 studies, representing 1400 participants. Attrition data were extracted for individual treatment conditions.

Validation of the Evidence-Based Practice Confidence (EPIC) Scale With Occupational Therapists.

Objective: This study evaluated the reliability, minimal detectable change (MDC), and construct validity of the Evidence-Based Practice Confidence (EPIC) scale among occupational therapists.

Method: In a cross-sectional mail survey, 126 occupational therapists completed the EPIC scale and a questionnaire to provide data for validity testing. Seventy-nine occupational therapists (63%) completed a second EPIC scale a median of 24 days later.

Medical professionalism: an experimental look at physicians' Facebook profiles.

Background: Use of social networking services (SNS) is on the rise. While many users sign in for personal purposes, it is not uncommon for professionals to connect over SNSs with clients, students, and patients.

Methods: The present study used an experimental approach to examine how medical doctors' SNS profiles impacted potential patients' impressions of professionalism.

Evolving capacity and decision-making in practice: adolescents' access to legal abortion services in Mexico City.

The rights of adolescents and young people in international law and agreements have evolved significantly from a focus on protection to a recognition of "evolving capacities" and decision-making ability. Unclear policies and regulations and variations in actual practice may leave providers with little clarity on how to support adolescent decision-making and instead create unintended barriers. This study in Mexico City in 2009 explored whether regulations and clinical attitudes and practice were supporting or hindering the access of adolescent girls aged 12-17 to information regarding abortion and to abortion services.

A biomechanical investigation of a knotless tension band in medial malleolar fracture models in composite Sawbones®.

The present study introduces a knotless tension band construct and compares its biomechanical behavior with that of a traditional stainless steel tension band construct. Fourth-generation composite tibial Sawbones(®) were used in the present study. Fracture models were created to mimic Orthopaedic Trauma Association type 44-B2.

Decisionmaking regarding unwanted pregnancy among adolescents in Mexico City: a qualitative study.

Adolescents in Latin America and the Caribbean confront difficult decisions when faced with unwanted pregnancies, especially given the region's legal restrictions on and widespread cultural opposition to abortion. Little research has been conducted on pregnancy decisionmaking among young people in this region. This study examines the role of peers, partners, family members, and health-care providers in adolescents' decisionmaking regarding pregnancy continuation or termination in Mexico City shortly after abortion was legalized in 2007.

Principal findings from a multicenter trial investigating the safety of follicular-fluid meiosis-activating sterol for in vitro maturation of human cumulus-enclosed oocytes.

Objective: To evaluate the safety of applying follicular-fluid meiosis-activating sterol (FF-MAS) in vitro to immature human oocytes.

Design: Phase I bicenter, randomized, parallel-group, controlled, partially blinded trial.

Setting: Third-level referral academic centers, including reproductive biology and genetics laboratories.

Phase II study of fludarabine and alpha-interferon in patients with low-grade non-Hodgkin's lymphoma.

Background And Objectives: Low-grade non-Hodgkin's lymphoma (NHL) remains incurable with standard dose chemotherapy. Nucleoside analogs such as fludarabine are effective, but even when used as initial therapy, the median duration of remission ranges from only 16 to 24 months. Interferon (IFN) is also active and has been investigated both by incorporating it into the chemotherapy regimen and/or as maintenance therapy, where it may prolong remission.

Karyotyping of human metaphase II oocytes by multifluor fluorescence in situ hybridization.

Objective: To quantify aneuploidy in inseminated, injected, and noninjected oocytes from infertility patients using Multifluor fluorescence in situ hybridization (M-FISH).

Design: Prospective study.

Setting: Reproductive biology group, academic unit of pediatrics, obstetrics, and gynecology.

Demonstration of a mechanism of aneuploidy in human oocytes using Multifluor fluorescence in situ hybridization.

Objective: To evaluate the potential of Multifluor fluorescence in situ hybridization (M-FISH) for karyotyping the human oocyte and first polar body.

Design: Prospective case study.

Setting: Research laboratories, university hospital.

Accuracy of stereotactic core-needle breast biopsy in atypical ductal hyperplasia.

Background: The histologic diagnosis of atypical ductal hyperplasia (ADH) has been reported as having a high rate of malignancy, either ductal carcinoma in situ (DCIS) or invasive ductal carcinoma (IDC). We reviewed our surgical group's experience with stereotactic core-needle biopsies (SCNB), specifically looking at the follow-up of ADH.

Methods: From November 1994 through July 1997 our group performed 539 SCNB.

Treating esophageal cancer with a combination of chemotherapy, radiation, and excision.

Background: Treatment of esophageal cancer has been primarily palliative. Recent studies have shown that preoperative combination chemo- and radiation therapy increases the effectiveness of surgical excision.

Patients And Methods: Beginning in 1990, 29 patients in the Spokane area were treated with preoperative chemo- and radiation therapy.

A survey of patients seen in consultant clinics in conservative dentistry at Edinburgh Dental Hospital in 1990.

A baseline study of referrals by letter to a department of conservative dentistry staffed purely by honorary consultants was conducted for one year. Distinct differences were found between the majority of patients referred from general practice and those referred from other sources. Principal reasons for referral were problems of tooth replacement, appearance, endodontics and tooth wear.

The effect of parathyroidectomy on bone mineral density in primary hyperparathyroidism.

Bone mineral density was studied before, and at one year after successful parathyroidectomy in six postmenopausal, three premenopausal females and one male with primary hyperparathyroidism. Dual photon absorptiometry was used to measure bone mineral density at the lumbar spine in all subjects, and at three areas of the hip in eight of the subjects. There was no significant change in bone mineral density at the lumbar spine after one year.

Effects of temperature on the anaesthetic potency of halothane, enflurane and ethanol in Daphnia magna (Cladocera: Crustacea).

1. The effects of temperature on the anesthetic potencies of halothane, enflurane and ethanol have been studied in the water flea Daphnia magna. 2.

Laparotomy and multiple system organ failure.

A retrospective review of laparotomies was undertaken to define the indications for abdominal procedures in patients with multiple system organ failure. This study suggests patients with (MSOF) must be thoroughly evaluated with non-invasive technology to determine the presence of an intra-abdominal septic focus prior to consideration of exploratory laparotomy.