Transcutaneous bilirubin in exclusively breastfed healthy term newborns up to 12 days of life.

Objective: To determine the curve of transcutaneous bilirubin in breastfed term neonates up to 12 days of life.

Methods: In a prospective cohort study, we performed a 12-day evaluation of 223 healthy, exclusively breastfed, appropriate-for-gestational-age neonates who roomed-in for at least 48 hours. Each newborn had forehead transcutaneous bilirubin and body weight measured at the end of 1, 2, 3, 4, 5, 6, 8, 10, and 12 days.

Public conceptions of schizophrenia in urban Brazil : symptom identification and causal attributions.

Objective: Little is known about public conceptions of mental disorders in Latin America and the Caribbean. The aim of this article is to assess how the population identifies symptoms of schizophrenia and the causes attributed to this disorder in the city of São Paulo, Brazil.

Method: A household survey was carried out in 2002 with a probabilistic sample of 500 individuals, residents of São Paulo with ages ranging from 18 to 65.

Multidimensional pain assessment of preterm newborns at the 1st, 3rd and 7th days of life.

Context And Objective: It is challenge to assess and treat pain in premature infants. The objective of this study was to compare the multidimensional pain assessment of preterm neonates subjected to an acute pain stimulus at 24 hours, 72 hours and seven days of life.

Design And Setting: Prospective cohort study, at Universidade Federal de São Paulo.

Exposure to marijuana during pregnancy alters neurobehavior in the early neonatal period.

Objective: To assess the neurobehavior of full-term neonates of adolescent mothers exposed to marijuana during pregnancy.

Study Design: This prospective cross-sectional study included full-term infants within 24 to 72 hours of life born to adolescent mothers at a single center in Brazil. Data on sociodemographic and obstetrical and neonatal characteristics were collected.

Tri-iodothyronine differentially induces Kupffer cell ED1/ED2 subpopulations.

Thyroid calorigenesis is carried out by activation of cytochrome-c oxidase, as well as by induction of mitochondrial and nuclear genes that code for cell respiratory apparatus components and uncoupling proteins. These effects operate increments in basal metabolic rate and also lead to increased production of oxygen and nitrogen reactive species in liver parenchymal cells. The hepatic antioxidant system is also compromised, since superoxide dismutase and catalase activities, glutathione content and lipid soluble antioxidants are reduced.

Influence of age, gender, body mass index, and functional capacity on heart rate variability in a cohort of subjects without heart disease.

We studied the time- and frequency-domain indexes of heart rate variability (HRV) in 653 patients without any evidence of heart disease relative to age, gender, heart rate, body mass index, and functional capacity. There was an inverse correlation of HRV with heart rate (p <0.001).

Reliability of two behavioral tools to assess pain in preterm neonates.

Context: One of the main difficulties in adequately treating the pain of neonatal patients is the scarcity of validated pain evaluation methods for this population.

Objective: To analyze the reliability of two behavioral pain scales in neonates.

Type Of Study: Cross-sectional.

Antenatal treatment with corticosteroids for preterm neonates: impact on the incidence of respiratory distress syndrome and intra-hospital mortality.

Context: Although the benefits of antenatal corticosteroids have been widely demonstrated in other countries, there are few studies among Brazilian newborn infants.

Objective: To evaluate the effectiveness of antenatal corticosteroids on the incidence of respiratory distress syndrome and intra-hospital mortality among neonates with a gestational age of less than 34 weeks.

Type Of Study: Cross-sectional.

Studies on functional and morphological aspects in human multinodular simple goiter tissues.

Samples from 2 different locations within the same euthyroid multinodular goiters (SMG) and normal (N) human thyroids were assayed for their content of DNA, thyroglobulin (Tg), and stable iodine (1), and determined the response of adenosine 3',5'-cyclic monophosphate (cAMP) to TSH and NaF. Quantitative morphological estimation of histological components in the thyroid was performed and correlated with functional parameters. Regardless the zonal evaluation, in SMG the mean (± SD) DNA content (⧎g/mg tissue) (1.