Publications by authors named "Clovis Alexandrino-Silva"

Background: We aimed to identify different categorical phenotypes based upon the DSM-V criteria of alcohol use disorders (AUD) among alcohol users who had at least one drink per week in the past year (n=948).

Methods: Data are from the São Paulo Megacity Mental Health Survey collected in 2005-2007, as part of the World Mental Health Survey Initiative. A latent class analysis of the 11 DSM-5-AUD criteria was performed using Mplus, taking into account complex survey design features.

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Background: Few studies have investigated symptomatic subtypes of depression and their correlates by gender.

Methods: Data are from the São Paulo Megacity Mental Health Survey. Symptom profiles of 1207 subjects (864 women; 343 men) based upon symptoms of the worst depressive episode in lifetime were examined through latent class analysis.

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Background: Medical students experience a lot of stress what may contribute to symptoms of depression. In this study we set out to look at the environmental factors which may be contributing in one medical school in Brazil.

Methods: We assessed depressive symptoms using Beck's Depression Inventory in 465 and 267 medical students in 2001 and 2006 respectively.

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Article Synopsis
  • Rapid population growth in megacities like São Paulo is linked to increased social inequality and mental disorders, with about 30% of adults reporting a mental health issue in the past year.
  • Most common disorders include anxiety (19.9%) and mood disorders (11%), with factors like exposure to violence and neighborhood deprivation influencing prevalence.
  • Only one-third of those with severe mental disorders sought treatment, indicating a critical gap in mental health care accessibility for vulnerable populations, particularly women and migrant men in deprived areas.
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Objectives: To examine the association of life events and social support in the broadly defined category of depression in late life.

Introduction: Negative life events and lack of social support are associated with depression in the elderly. Currently, there are limited studies examining the association between life events, social support and late-life depression in Brazil.

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Although venlafaxine is usually associated with modest increases in blood pressure and not so often clinical hypertension, there are a few reported cases of hypotension related to overdoses of this specific antidepressant. The case study of a young female patient with a history of Major Depressive Disorder who initiated treatment with venlafaxine 75 mg/day and developed hypotension when the dosage was titrated up to 225 mg/day is described. The patient did not present comorbid diseases nor use other medication.

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