Long-term renal function following radical cystectomy and ileal conduit creation.

Background: Treatment for bladder cancer includes radical cystectomy (RC) and urinary diversion; RC is associated with long-term morbidity, kidney impairment and mortality.

Aim: To identify risk factors associated with postoperative long-term kidney function and mortality.

Methods: Retrospective study of patients with RC and urinary diversion in Beaumont Hospital from 1996 to 2016.

ANCA-associated vasculitis in Ireland: a multi-centre national cohort study.

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare multisystem autoimmune disease. There is a need for interoperable national registries to enable reporting of real-world long-term outcomes and their predictors in AAV. The Irish National Rare Kidney Disease (RKD) registry was founded in 2012.

The utility of a genetic kidney disease clinic employing a broad range of genomic testing platforms: experience of the Irish Kidney Gene Project.

Background And Aims: Genetic testing presents a unique opportunity for diagnosis and management of genetic kidney diseases (GKD). Here, we describe the clinical utility and valuable impact of a specialized GKD clinic, which uses a variety of genomic sequencing strategies.

Methods: In this prospective cohort study, we undertook genetic testing in adults with suspected GKD according to prespecified criteria.