In vitro simulation of the first technique for non-invasive measurement of volumetric ophthalmic artery blood flow in humans.

Background And Objective: To evaluate the accuracy, reproducibility, and variability of volumetric flow measurements taken by color Doppler imaging ultrasound, using an in vitro "phantom" model to simulate the ophthalmic artery.

Materials And Methods: An agar flow phantom with two wall-less lumens was constructed to simulate the ophthalmic artery. Velocity and volumetric flow measurements were taken for various flow rates and ultrasound probe positions.

Diagnostic ability of Fourier-domain vs time-domain optical coherence tomography for glaucoma detection.

Purpose: To compare retinal nerve fiber layer (RNFL) thickness assessments and the discriminating ability of Fourier-domain optical coherence tomography (FD-OCT) with that of time-domain optical coherence tomography (TD-OCT) for glaucoma detection.

Design: Prospective, nonrandomized, observational cohort study.

Methods: Normal and glaucomatous eyes underwent complete examination, standard automated perimetry, optic disc photography, TD-OCT (Stratus OCT; Carl Zeiss Meditec, Dublin, California, USA), and FD-OCT (RTVue; Optovue Inc, Fremont, California, USA).

Ocular toxoplasmosis presenting with focal retinal nerve fiber atrophy simulating glaucoma.

Purpose: We describe a patient with ocular hypertension and nonglaucomatous retinal nerve fiber layer (RNFL) atrophy associated with an ocular toxoplasmosis retinal lesion.

Patient And Method: Single case report.

Results: An RNFL defect was identified adjacent to a circumscribed pigmented chorioretinal lesion superior to the macular region.

Migration of glaucoma drainage device extender into anterior chamber after trauma.

Purpose: Glaucoma drainage devices, on rare occasions, need repositioned and the intraocular portion of the implant tube is found to be "too short" to do so. Previously, a technique was described for "extending" the tube with angiocatheter material (rather than replacing the entire apparatus), and had been performed successfully without complication for 7 years. This case describes the first known complication: trauma causing anterior chamber migration of the tube extension requiring retrieval and reconstruction of the tube extension apparatus.

Comparison of ocular hemodynamics measured by a new retinal blood flowmeter and color Doppler imaging.

Background And Objective: To compare measurements of a new retinal blood flow device with central retinal artery blood velocity.

Materials And Methods: One randomly selected eye from each of 13 subjects was examined. Blood flow was measured by laser blood flowmeter and velocity by color Doppler imaging.

Reduced cerebrovascular blood flow velocities and vasoreactivity in open-angle glaucoma.

Purpose: To compare cerebral blood flow velocities between open-angle glaucoma (OAG) patients and controls, at baseline and during hyperoxia.

Design: Observational cohort study.

Methods: A prospective study was conducted in a single institution.