Non-contact scintillator imaging dosimetry for total body irradiation in radiotherapy.

The goal of this work was to assess the potential use of non-contact scintillator imaging dosimetry for tracking delivery in total body irradiation (TBI).. Studies were conducted to measure the time-gated light signals caused by radiation exposure to scintillators that were placed on tissue.

The Effect of Mouse Size on Dose from an X-Rad320 Irradiator.

Irradiation protocols for murine experiments often use standardized dose rate estimates for calculating dose delivered, regardless of physical variations between mouse subjects. This work sought to determine the significance of mouse size on absorbed dose. Five mouse-like phantoms of various sizes based on the mouse whole-body (MOBY) model were 3D printed.

LET response variability of Gafchromic EBT3 film from a Co calibration in clinical proton beam qualities.

Purpose: To establish a method of accurate dosimetry required to quantify the expected linear energy transfer (LET) quenching effect of EBT3 film used to benchmark the dose distribution for a given treatment field and specified measurement depth. In order to facilitate this technique, a full analysis of film calibration which considers LET variability at the plane of measurement and as a function of proton beam quality is demonstrated. Additionally, the corresponding uncertainty from the process was quantified for several measurement scenarios.

Dosimetric characterization of a new directional low-dose rate brachytherapy source.

Purpose: CivaTech Oncology Inc. (Durham, NC) has developed a novel low-dose rate (LDR) brachytherapy source called the CivaSheet. The source is a planar array of discrete elements ("CivaDots") which are directional in nature.

An interlaboratory comparison of dosimetry for a multi-institutional radiobiological research project: Observations, problems, solutions and lessons learned.

Purpose: An interlaboratory comparison of radiation dosimetry was conducted to determine the accuracy of doses being used experimentally for animal exposures within a large multi-institutional research project. The background and approach to this effort are described and discussed in terms of basic findings, problems and solutions.

Methods: Dosimetry tests were carried out utilizing optically stimulated luminescence (OSL) dosimeters embedded midline into mouse carcasses and thermal luminescence dosimeters (TLD) embedded midline into acrylic phantoms.

Radiation Biology Irradiator Dose Verification Survey.

Interest in standardized dosimetry for radiobiological irradiators has expanded over the last decade. At a symposium held at NIST, "The Importance of Standardization of Dosimetry in Radiobiology", a set of 12 criteria necessary for adequate irradiation was developed by the authors. Here we report on our review of dosimetry methods from various peer-reviewed publications and found that none of them satisfied all 12 criteria set forth by the authors of the NIAD/NCI/NIST proceedings.