Genotoxic effect induced by dried leaves from tobacco barns (kiln-houses) in chinese hamster lung fibroblast cells (V79).

is the most cultivated tobacco species in the state of Rio Grande do Sul, Brazil. Workers who handle the plant are exposed to the leaf components during the harvesting process and when separating and classifying the dried leaves. In addition to nicotine, after the drying process, other components may be found including tobacco-specific nitrosamines, polycyclic aromatic hydrocarbons, as well as pesticides residues.

Evaluation of the cytotoxic and genotoxic effects of Cav extract using human neuroblastoma cell line SH-SY5Y.

is a weed thought to have originated in Brazil, where it is present in abundant quantities, but also this plant is also found in south-central Florida, Indian Ocean Islands, and the Pacific Islands. produces neurotoxicity that adversely affects livestock breeding with heavy animal losses and consequent negative impact on Brazil's economy. The aim of this study was to determine the chemical profile, cytotoxic and genotoxic effects of ethanolic extracts of collected in winter (leaf extract) and summer (leaf extract and leaf + flower extract) using an model of human neuroblastoma cell line SH-SY5Y.