[Primary pulmonary hypertension--morphologic study].

Primary pulmonary hypertension is characterized by elevation of pulmonary arterial pressure over 25 mm Hg with increasing of pulmonary vascular resistance. Primary pulmonary hypertension is the result of idiopathic narrowing of pulmonary arteries and extensive remodeling of the pulmonary vasculature in case of lack of the pulmonary interstitial disease, cardiac diseases, and pulmonary thromboembolism. The morphological study revealed the histological vascular elements characteristic in arterial hypertension (intimal proliferation, medial hypertrophy, plexiform and dilatative lesions) associated with recent and organized arterial thrombosis secondary to intimal lesions through a recent infectious process.

Morphological evaluation of the surgically removed aortic and mitral valves.

In 2001, of the 114 valves surgically excised at the Iaşi Center of Cardiology from 59 men and 54 women (mean age 51 years; age range: 25 to 78 years), half were aortic and the other half mitral valves. The 57 aortic valves, from 20 women and 37 men (mean age 51.1; age range 25 to 78 years), had been surgically replaced.

Two cases of Marfan syndrome.

The early identification of the Marfan Syndrome should be essential for the prevention of the aortic dilatation and dissection, but the wide phenotypic expression of the disorder makes the clinical diagnosis very difficult. The aim of this study is to emphasise the necessity of a widely applicable method of morpho-clinical diagnosis. The diagnosis was confirmed on surgical biopsies from ascending aortic wall and aortic cusps, using routine morphological techniques.

[Morphologic and clinical correlations in medullar thymoma].

The medullar thymoma is a rare and distinctive epithelial thymoma, a thymic tumor characterized histologically by a mixture of spindle epithelial cells and lymphoid cells. We are presenting this tumor to a 68 years old man, admitted at CCI, for a mediastinal tumor, treated by tumorectomy, for revealing the cytological, histological and immunohistochemical characteristic features. The surgical biopsy was prepared by using usual histological techniques and haematoxilin eosin and Van Gieson stainings.

Cardiac leiomyosarcoma. Case report.

A case of primary cardiac leiomyosarcoma diagnosed at Iaşi Cardiology Center is presented. The study was made on the surgical biopsy specimen, and the diagnosis by routine morphological techniques. The gross examination revealed a large intracavitary left atrial tumor attached by a small sessile base to the left posterior atrial wall, having a smooth, white-gray surface, and a dense consistency.