Publications by authors named "Clement Lai"

Introduction: The study sought to assess the cost-effectiveness of silver diamine fluoride (SDF) relative to sodium fluoride (NaF) varnish and direct restorations placed chairside or under general anaesthesia, accounting for caries activity.

Methods: An analytical decision-tree model was developed with clinical data from multiple centres to evaluate the four treatment options among all children aged 1-6 years in Singapore (N = 231,880) over a 12-month time horizon. Base-case scenarios consisted of children with low (1 carious tooth)- and high (7 carious teeth)-caries activity.

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Objective: This systematic review and meta-analysis aimed to determine the implications of implant design on the outcomes of simultaneous guided bone regeneration (GBR) to correct dehiscence defects.

Methods: A structured search strategy was applied to MEDLINE (PubMed), Cochrane Library, and Embase, to identify prospective clinical trials involving implants with simultaneous GBR to correct dehiscence defects. Data regarding implant characteristics, GBR materials, as well as dehiscence defect dimensions at implant placement and surgical re-entry was collected.

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This study evaluated in vivo, an intraoral device against the gold standard esophageal device for gastroesophageal reflux disease (GERD) monitoring. Subjects scheduled for a catheter-based esophageal pH/impedance testing at a gastroenterology clinic were recruited. They were screened using the GerdQ questionnaire, demographics and dental conditions recorded.

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Background: Jaw osteoradionecrosis (ORN) is a complication in patients with previous head and neck radiotherapy. Its incidence increases with dental extractions. Hence, this review aimed to evaluate the efficacy of adjunctive treatment modalities undertaken at the time of extraction in previous head and neck radiotherapy patients in preventing ORN.

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Article Synopsis
  • The study investigates the effectiveness of VY closure compared to conventional continuous closure (CS) in preventing lip shortening after Le Fort 1 maxillary advancements.
  • A systematic review of 487 articles led to the inclusion of six studies, showing that VY closure doesn’t reliably prevent lip shortening, though it may have benefits for larger maxillary advancements.
  • Results indicated that VY closure often results in a more protrusive lip appearance due to increased lip vermillion exposure, so surgeons should consider individual aesthetic preferences when choosing this technique.
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Objectives: To evaluate the efficacy of probiotics in reducing halitosis of dental origin.

Methods: MEDLINE, EMBASE, and CENTRAL were searched up to and including June 2020. Randomised placebo-controlled, double-blinded clinical trials in systemically healthy adult patients who were given any form of probiotics to manage halitosis of dental origin were included.

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Article Synopsis
  • Ridge preservation is effective, but there's limited evidence on how different surgical techniques impact outcomes.
  • Flapless techniques may better maintain soft tissue architecture and show promise for managing mild to moderate defects with less than 50% buccal bone loss.
  • A review of studies revealed that flapless techniques significantly reduce hard tissue changes, but their impact on soft tissue changes remains unclear, indicating a need for more research.
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Introduction: Nonsurgical endodontic retreatment and apical surgery are predictable procedures for the management of endodontically treated teeth with persistent disease. However, there is no information available that compares these treatment modalities based on patients' oral health-related quality of life (OHRQOL). The aims of this study were to compare the OHRQOL of patients who received nonsurgical endodontic retreatment versus those who received apical surgery and to identify correlations between OHRQOL, clinician-assessed healing outcome, and other factors.

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Background And Aims: The success rate of unguided nasojejunal feeding tube insertion is low, thus often requiring endoscopic or radiological assistance. The spiral end of the Bengmark nasojejunal tube is supposed to aid post-pyloric placement, but no comparative trial has been performed.

Methods: Patients requiring nasojejunal feeding were randomised to have either Medicina (straight) or Bengmark (spiral) nasojejunal tube placed after stratification into those with normal gastric emptying or clinical evidence of delayed gastric emptying.

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