Publications by authors named "Clemens Vogel"

Objective: Intraoperative neuropathological assessment with conventional frozen sections supports the neurosurgeon in optimizing the surgical strategy. However, preparation and review of frozen sections can take as long as 45 minutes. Stimulated Raman histology (SRH) was introduced as a novel technique to provide rapid high-resolution digital images of unprocessed tissue samples directly in the operating room that are comparable to conventional histopathological images.

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Currently, approximately 150 different brain tumour types are defined by the WHO. Recent endeavours to exploit machine learning and deep learning methods for supporting more precise diagnostics based on the histological tumour appearance have been hampered by the relative paucity of accessible digital histopathological datasets. While freely available datasets are relatively common in many medical specialties such as radiology and genomic medicine, there is still an unmet need regarding histopathological data.

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Article Synopsis
  • Acupuncture is commonly used for pain relief, but there is limited evidence from rigorous studies to support its effectiveness compared to placebo.
  • A study was conducted with 50 healthy men using two pain models to compare traditional acupuncture with sham acupuncture, focusing on pain intensity reduction.
  • The findings indicated a small and clinically questionable reduction in pain specifically after capsaicin injection, but no significant differences were found during the cold-pressor test or other pain-related measures, leading to the conclusion that acupuncture has a minor effect on experimental pain in this population.
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