Publications by authors named "Clemens Alexander Klaus Lange"
Article Synopsis
- The study aimed to analyze the expression of HIF-1α and its effects on various types of tumors in the ocular adnexa to assess its role as a potential prognostic indicator.
- Researchers examined 49 patients with malignant tumors (like squamous cell carcinomas, non-Hodgkin lymphomas, and melanomas) and compared them with 30 patients with benign tumors, using methods like immunohistochemistry and transcriptomic analysis.
- Results showed that SCC tumors had significantly higher HIF-1α expression compared to benign tumors, and elevated HIF-1α levels correlated with a potentially worse prognosis for malignant cases, implicating its involvement in tumor growth and spread.
