Publications by authors named "Clemence Boully"

Article Synopsis
  • Lumbar puncture (LP) is a key diagnostic tool often avoided in older adults due to fears of complications, particularly among healthcare teams unfamiliar with the procedure.
  • A qualitative study involving interviews with cognitively impaired patients over 70, their relatives, and healthcare teams aimed to gather perspectives on scheduled LP experiences.
  • Findings revealed a poor understanding of LP among patients, who had exaggerated fears about risks and pain, while both relatives and healthcare teams expressed a desire for accurate diagnoses, indicating a gap in knowledge and communication surrounding the procedure.
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Objective: The role of treatment with renin-angiotensin-aldosterone system blockers at the onset of COVID-19 infection is not known in the geriatric population. The aim of this study was to assess the relationship between angiotensin receptor blockers (ARBs) and angiotensin-converting enzyme inhibitor (ACEI) use and in-hospital mortality in geriatric patients hospitalized for COVID-19.

Design: This observational retrospective study was conducted in a French geriatric department.

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Article Synopsis
  • A multicentric study in Paris analyzed characteristics and outcomes of 821 hospitalized patients aged 70 and older with confirmed COVID-19 from March to April 2020.
  • Patients had a mean age of 86, with 85% having two or more pre-existing health conditions, and exhibiting common symptoms such as asthenia, fever, and dyspnea.
  • The in-hospital mortality rate was 31%, with factors like male gender, lower functional status, and specific health anomalies increasing the likelihood of death, highlighting the importance of early risk assessment for older patients.
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Background: To evaluate the prevalence and management of heart failure (HF) in very old patients in geriatric settings.

Methods: Members of the French Society of Geriatrics and Gerontology throughout France were invited to participate in a point prevalence survey and to include all patients ≥80 years old, hospitalized in geriatric settings, with HF (stable or decompensated) on June 18, 2012. General characteristics, presence of comorbidities, blood tests and medications were recorded.

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To examine the antihypertensive efficacy and safety of indapamide sustained-release (SR)/amlodipine compared with enalapril/amlodipine in patients 65 years and older with uncontrolled blood pressure (BP) on monotherapy, a post hoc analysis of the NESTOR trial (Natrilix SR vs Enalapril in Hypertensive Type 2 Diabetics With Microalbuminuria) was conducted. NESTOR randomized 570 patients (n=197, aged ≥65 years) with hypertension (systolic BP 140-180/diastolic BP <110 mm Hg) to indapamide SR 1.5 mg or enalapril 10 mg.

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Aims: To evaluate the interest of brain natriuretic peptide (BNP) for heart failure (HF) diagnosis in very old patients.

Methods And Results: A total of 383 patients aged 80 years or older, hospitalized in geriatrics care for dyspnoea, had a BNP measurement at the acute phase. Independent cardiologists blinded to BNP values classified the patients into cardiac vs.

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Background: A fall in elderly subjects can lead to serious psychological consequences. These symptoms can develop into Fear of Falling with behavioural disorders comparable to PTSD that may severely limit autonomy. Virtual reality training (VRT) could be seen as a worthwhile therapeutic approach for this syndrome since it has been shown to be a useful tool for motor rehabilitation or combat-related PTSD.

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[Heart failure and comorbidities].

Geriatr Psychol Neuropsychiatr Vieil

March 2015

Heart failure is a frequent disease in the elderly. Its clinical presentation is less typical and the prognosis more severe than in younger subjects because heart failure occurs in patients with multiple comorbidities. A comprehensive geriatric assessment should therefore be performed to detect the vulnerabilities and manage the comorbidities.

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There are a number of causes of falls in the elderly. The psychological trauma following a fall can be significant and require early care management. There are multidisciplinary prevention strategies which must be adapted to each case.

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Background: Combination treatments for hypertension most often include a renin-angiotensin-aldosterone system (RAAS) inhibitor. However, systolic blood pressure (SBP) remains difficult to control. Non-RAAS-inhibiting strategies such as calcium channel blocker/thiazide-like diuretic combinations may offer effective alternatives.

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Objectives: Home blood pressure measurement (HBPM) is recommended by guidelines for hypertension management. However, this method might be difficult to use in elderly individuals with cognitive disorders. Our aim was to assess the agreement and the feasibility of HBPM by a relative as compared with 24-h ambulatory blood pressure monitoring (ABPM) in elderly patients with dementia.

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