Parkinson Anxiety Scale: A Validation Study for the Brazilian Population.

Objective: The Parkinson Anxiety Scale (PAS) was developed to measure the severity of anxiety symptoms in patients with Parkinson's disease (PD), and it has not yet been adapted and validated in Portuguese. Thus, this study evaluated the reliability and validity of a translated and adapted version of the PAS for the Brazilian population of PD patients.

Methods: The Parkinson Anxiety Scale - Brazilian Version (PAS-BV) was completed by 55 patients with PD.

Resistance training reduces depressive symptoms in elderly people with Parkinson disease: A controlled randomized study.

Background: Depression affects up to 40% of individuals with Parkinson's disease (PD).

Purpose: To assess resistance training effects on the depressive symptoms of elderly PD patients.

Study Design: A randomized control study.

Strength training improves the respiratory muscle strength and quality of life of elderly with Parkinson disease.

Background: The progression of Parkinson disease can lead to respiratory muscle weakness, reduced peak expiratory flow and quality of life (QoL). The aim was to evaluate the effects of strength training on levels of respiratory muscle strength, peak expiratory flow and QoL of elderly with Parkinson disease.

Methods: A total of 28 patients were randomized into one of two groups: the control group (CG) comprised 16 participants, and the strength training group (STG) comprised 12 participants.

Low-volume resistance training improves the functional capacity of older individuals with Parkinson's disease.

Aim: To evaluate the effects of low-volume resistance training on the physical and functional capacity of older patients with Parkinson's disease.

Methods: A total of 54 patients (aged ≥60 years) were randomly divided into two groups: (i) a control group comprising 13 men and 14 women; and (ii) a resistance training group with 14 men and 13 women. The resistance training group, in addition to maintaining their pharmacological treatments, carried out 6 months of resistance training twice a week, whereas the control group maintained their pharmacological treatments.

The effect of resistance training on the anxiety symptoms and quality of life in elderly people with Parkinson's disease: a randomized controlled trial.

Objectives: To assess the effects of resistance training on the anxiety symptoms and quality of life in patients with Parkinson's disease.

Methods: Thirty-five elderly patients were randomly divided into two groups: 17 patients in the control group and 18 in the intervention group. All patients maintained standard pharmacological treatment for Parkinson's disease, but the intervention group participated in a 24-week resistance training program.

Does the Polymorphism in the Length of the Polyalanine Tract of Gene Influence the Risk of Thyroid Dysgenesis Occurrence?

Recent data have suggested that polymorphisms in the length of the polyalanine tract (polyA) of gene may act as a susceptibility factor for thyroid dysgenesis. The main purpose of this study was to investigate the influence of polyA of gene on the risk of thyroid dysgenesis. A case-control study was conducted in a sample of 90 Brazilian patients with thyroid dysgenesis and 131 controls without family history of thyroid disease.

High frequency of D727E polymorphisms in exon 10 of the TSHR gene in Brazilian patients with congenital hypothyroidism.

Congenital Hypothyroidism affects between 1:3000 and 1:4000 newborn infants in iodine-sufficient regions. Some studies have shown that mutations and polymorphisms in the TSH receptor gene are responsible for this disease. In the present study, mutations of exon 10 of the TSH receptor gene were investigated in Congenital Hypothyroidism patients.