Defect engineering in organic semiconductor based metal-dielectric photonic crystals.

We investigate the band structure of metal-dielectric photonic crystals comprising stacked organic semiconductor microcavities with silver metal mirrors incorporating crystal defects: individual unit cells with aperiodic dimensionality. Both transfer matrix simulation and experimental verification are performed to investigate the impact on the photonic band structure as a single cavity is varied in size. The resulting mid-gap defect states are shown to hybridize with a photonic band at certain resonant dimensions.

Visual and Anatomic Responses in Patients With Neovascular Age-Related Macular Degeneration and a Suboptimal Response to Anti-VEGF Therapy Switched to Faricimab.

To determine the efficacy of switching to intravitreal (IVT) faricimab in patients with treatment-resistant neovascular age-related macular degeneration (nAMD) and determine the rates of reversion to original antivascular endothelial growth factor (anti-VEGF) therapy. A retrospective chart review was performed of patients with nAMD and persistent fluid on optical coherence tomography previously treated with anti-VEGF injections who received at least 1 IVT faricimab injection between March 1, 2022, and January 31, 2023. The study comprised 135 eyes of 119 patients.

Using Self-Regulated Learning Microanalysis to Examine Regulatory Processes in Clerkship Students Engaged in Practice Questions.

Introduction: Self-regulated learning is a cyclical process of forethought, performance, and self-reflection that has been used as an assessment tool in medical education. No prior studies have evaluated SRL processes for answering multiple-choice questions (MCQs) and most evaluated one or two iterations of a non-MCQ task. SRL assessment during MCQs may elucidate reasons why learners are successful or not on these questions that are encountered repeatedly during medical education.

Hwiccewyrm trispiculum gen. et sp. nov., a new leptopleuronine procolophonid from the Late Triassic of southwest England.

The fissure fill localities of southwest England and South Wales are well-known for preserving rich assemblages of predominantly small-bodied Late Triassic to Early Jurassic tetrapods, but many aspects of these assemblages remain contentious. The age of the Late Triassic fissures is disputed, with some lines of argument suggesting a latest Triassic (Rhaetian) age, whereas other evidence suggests they may be as old as Carnian. The fissures have been hypothesized by some workers to have formed on an archipelago, with island effects invoked to explain aspects of the assemblages such as the abundance of small-bodied species.

The effect of dance on physical health and cognition in community dwelling older adults: A systematic review and meta-analysis.

Background: Dancing is an attractive form of exercise among older adults and may positively influence physical and psychosocial health. The aim of this systematic review was to synthesize the evidence examining the dance prescription and effectiveness of dance in community dwelling older adults.

Methods: Eight databases were searched to identify randomized controlled trials that evaluated the effectiveness of dance programs on community-dwelling older adults from 2007 to December 2020.

P-Flash - A Machine Learning-based Model for Flashover Prediction using Recovered Temperature Data.

Research was conducted to examine the use of Support Vector Regression (SVR) to build a model to forecast the potential occurrence of flashover in a single-floor, multi-room compartment fire. Synthetic temperature data for heat detectors in different rooms were generated, 1000 simulation cases are considered, and a total of 8 million data points are utilized for model development. An operating temperature limitation is placed on heat detectors where they fail at a fixed exposure temperature of 150 °C and no longer provide data to more closely follow actual performance.

Insights from an early-stage development mixed methods study on arts-based interventions for older adults following hospitalisation.

Background: A period of hospitalisation can have negative consequences on physical function and autonomy for older adults, including functional decline, dependency and reduced quality of life. Older adults favour activity that focuses on social connectedness, fun and achievable skills.

Objective: The primary aim of this early-stage development mixed methods study was to determine the feasibility and acceptability of a randomised crossover trial design and two arts-based interventions tailored for older adults recently discharged from hospital.

Effects of live and video simulation on clinical reasoning performance and reflection.

Introduction: In recent years, researchers have recognized the need to examine the relative effectiveness of different simulation approaches and the experiences of physicians operating within such environments. The current study experimentally examined the reflective judgments, cognitive processing, and clinical reasoning performance of physicians across live and video simulation environments.

Methods: Thirty-eight physicians were randomly assigned to a live scenario or video case condition.

The apparent exponential radiation of Phanerozoic land vertebrates is an artefact of spatial sampling biases.

There is no consensus about how terrestrial biodiversity was assembled through deep time, and in particular whether it has risen exponentially over the Phanerozoic. Using a database of 60 859 fossil occurrences, we show that the spatial extent of the worldwide terrestrial tetrapod fossil record itself expands exponentially through the Phanerozoic. Changes in spatial sampling explain up to 67% of the change in known fossil species counts, and these changes are decoupled from variation in habitable land area that existed through time.

First-year medical students' calibration bias and accuracy across clinical reasoning activities.

To be safe and effective practitioners and learners, medical professionals must be able to accurately assess their own performance to know when they need additional help. This study explored the metacognitive judgments of 157 first-year medical students; in particular, the study examined students' self-assessments or calibration as they engaged in a virtual-patient simulation targeting clinical reasoning practices. Examining two key subtasks of a patient encounter, history (Hx) and physical exam (PE), the authors assessed the level of variation in students' behavioral performance (i.

Diversity dynamics of Phanerozoic terrestrial tetrapods at the local-community scale.

The fossil record provides one of the strongest tests of the hypothesis that diversity within local communities is constrained over geological timescales. Constraints to diversity are particularly controversial in modern terrestrial ecosystems, yet long-term patterns are poorly understood. Here we document patterns of local richness in Phanerozoic terrestrial tetrapods using a global data set comprising 145,332 taxon occurrences from 27,531 collections.

Clinical Reasoning Assessment Methods: A Scoping Review and Practical Guidance.

Purpose: An evidence-based approach to assessment is critical for ensuring the development of clinical reasoning (CR) competence. The wide array of CR assessment methods creates challenges for selecting assessments fit for the purpose; thus, a synthesis of the current evidence is needed to guide practice. A scoping review was performed to explore the existing menu of CR assessments.

Measurements and predictions of thermophoretic soot deposition.

A thin laminar flow channel with a transverse temperature gradient was used to examine thermophoretic deposition of soot aerosol particles in experiments and modeled in Fire Dynamics Simulator (FDS) simulations. Conditions investigated included three flowrates, with nominal Reynolds number based on the hydraulic diameter of 55, 115 and 230, and two applied temperature gradients, nominally 10 °C/mm and 20 °C/mm, with repeats. Soot was generated from a propene diffusion flame.

Lepidosaurian diversity in the Mesozoic-Palaeogene: the potential roles of sampling biases and environmental drivers.

Lepidosauria is a speciose clade with a long evolutionary history, but there have been few attempts to explore its taxon richness through time. Here we estimate patterns of terrestrial lepidosaur genus diversity for the Triassic-Palaeogene (252-23 Ma), and compare observed and sampling-corrected richness curves generated using Shareholder Quorum Subsampling and classical rarefaction. Generalized least-squares regression (GLS) is used to investigate the relationships between richness, sampling and environmental proxies.

Complex Infections: A Retrospective Cohort Study.

Background: Infections caused by group strains are usually resistant to multiple antimicrobials and challenging to treat worldwide. We describe the risk factors, treatment, and clinical outcomes of patients in 2 large academic medical centers in the United States.

Methods: A retrospective cohort study of hospitalized adults with a positive culture for in Miami, Florida (January 1, 2011, to December 31, 2014).

Evaluation of Spacecraft Smoke Detector Performance in the Low-Gravity Environment.

In the interest of fire prevention, most materials used in the interior construction of manned spacecraft are non-flammable, however, they do produce smoke when overheated. Spacecraft smoke detectors will ideally detect smoke generated by oxidative pyrolysis (such as smoldering) in order to allow the maximum time for the crew to respond before a larger flaming fire develops. An experiment on the International Space Station (ISS) characterized smoke from overheating common spacecraft materials.

Effects of the Self-Regulation Empowerment Program (SREP) on middle school students' strategic skills, self-efficacy, and mathematics achievement.

The current study examined the effectiveness of an applied self-regulated learning intervention (Self-Regulation Empowerment Program (SREP)) relative to an existing, school-based remedial mathematics intervention for improving the motivation, strategic skills, and mathematics achievement of academically at-risk middle school students. Although significant group differences in student self-regulated learning (SRL) were not observed when using self-report questionnaires, medium to large and statistically significant group differences were observed across several contextualized, situation-specific measures of strategic and regulatory thinking. The SREP group also exhibited a statistically significant and more positive trend in achievement scores over two years in middle school relative to the comparison condition.

Effect of intravitreal aflibercept on recalcitrant diabetic macular edema.

Background: Despite anti-VEGF therapy, some patients develop chronic diabetic macular edema. The objective of this study was to evaluate anatomic and visual outcomes of switching patients with chronic DME from intravitreal bevacizumab or ranibizumab to intravitreal aflibercept injection.

Methods: In this retrospective observational case series, 11 eyes with recalcitrant diabetic macular edema (DME) were evaluated 6 months prior to and 6 months following initial intravitreal aflibercept injection (IAI).

Multidimensional assessment of self-regulated learning with middle school math students.

This study examined the convergent and predictive validity of self-regulated learning (SRL) measures situated in mathematics. The sample included 100 eighth graders from a diverse, urban school district. Four measurement formats were examined including, 2 broad-based (i.

Microanalytic Assessment of Self-Regulated Learning During Clinical Reasoning Tasks: Recent Developments and Next Steps.

Helping medical educators obtain and use assessment data to assist medical students, residents, and physicians in reducing diagnostic errors and other forms of ineffective clinical practice is of critical importance. Self-Regulated Learning-Microanalytic Assessment and Training is an assessment-to-intervention framework designed to address this need by generating data about trainees' strategic processes (e.g.

High Prevalence and Increased Severity of Norovirus Mixed Infections Among Children 12-24 Months of Age Living in the Suburban Areas of Lima, Peru.

In an active diarrhea surveillance study of children aged 12-24 months in Lima, Peru, norovirus was the most common pathogen identified. The percentage of mixed (bacterial and noroviral) infections was significantly higher among norovirus-positive samples (53%) than among norovirus-negative samples (12%). The combination of norovirus with the most common bacterial pathogens was associated with increased clinical severity over that of either single-pathogen norovirus or single-pathogen bacterial infections.

pic gene of enteroaggregative Escherichia coli and its association with diarrhea in Peruvian children.

Enteroaggregative Escherichia coli (EAEC) causes acute and persistent diarrhea among children, HIV-infected patients, and travelers to developing countries. We have searched for 18 genes-encoding virulence factors associated with aggregative adherence, dispersion, biofilm, toxins, serine protease autotransporters of Enterobacteriaceae (SPATEs) and siderophores, analyzed in 172 well-characterized EAEC strains (aggR(+)) isolated from stool samples of 97 children with diarrhea and 75 healthy controls from a passive surveillance diarrhea cohort study in Peru. Eighty-one different genetic profiles were identified, 37 were found only associated with diarrhea and 25 with control samples.

Carbapenem-Resistant Acinetobacter baumannii: Concomitant Contamination of Air and Environmental Surfaces.

OBJECTIVE To concomitantly determine the differential degrees of air and environmental contamination by Acinetobacter baumannii based on anatomic source of colonization and type of ICU layout (single-occupancy vs open layout). DESIGN Longitudinal prospective surveillance study of air and environmental surfaces in patient rooms. SETTING A 1,500-bed public teaching hospital in Miami, Florida.

Contamination of Ambient Air with Acinetobacter baumannii on Consecutive Inpatient Days.

Acinetobacter-positive patients had their ambient air tested for up to 10 consecutive days. The air was Acinetobacter positive for an average of 21% of the days; the rate of contamination was higher among patients colonized in the rectum than in the airways (relative risk [RR], 2.35; P = 0.