Polycarbonate (PC) is a highly versatile plastic material that is extensively utilized across various industries due to its superior properties, including high impact strength and heat resistance. However, its durability presents significant challenges for recycling and waste management. Polycarbonate is a thermoplastic polymer representative of the class of condensation reaction polymers obtained from the reaction of bisphenol A (BPA) and a carbonyl source, such as phosgene or alkyl and aryl carbonate.
View Article and Find Full Text PDFEnvironmental pollution is a serious threat to human health and the natural environment, and it has aroused widespread concern. One of the most effective processes in the removal of pollutants from wastewater is the Fenton reaction. This process is based on the production of highly reactive •OH radicals due to the rapid reaction between Iron ions and hydrogen peroxide under acidic conditions.
View Article and Find Full Text PDFWe investigated the occurrence of organochlorine pollutants (OCs) in the muscle of brown trout and evaluated their potential modulation of parasite infection. The toxicological risk for consumer health was assessed, too. Trout were collected from the Sila National Park (Calabria region, South of Italy).
View Article and Find Full Text PDFWater potabilization sludges (WPS) are a heterogeneous waste generated from the coagulation-flocculation process of drinking water production, whose composition is highly dependent on the geological context of reservoirs, the composition and volume of treated water, and the types of coagulants used. For this reason, any feasible approach for reusing and valorising of such waste cannot be disregarded from the detailed investigation of its chemical and physical characteristics and they have to be evaluated at a local scale. In this study, WPS samples from two plants serving the Apulian territory (Southern Italy) were subjected for the first time to a detailed characterization with a view to evaluating their recovery and reuse at a local scale as a raw material for producing alkali activated binders.
View Article and Find Full Text PDFThis work deals with the investigation of alkaline binders obtained from binary mixtures of carbonate-rich illitic clay from deposits in southern Italy and two industrial by-products with very different total composition and calcium content, i.e., blast furnace slag and type F fly ash, respectively.
View Article and Find Full Text PDFThe aim of the present study is to provide information about the ability of to survive within wild boar () meat and meat-based preparations and the duration of this survival, and to consider the preservation of its infectious potential toward humans and animals. Meat samples were artificially contaminated with an field strain and then stored at -20 °C, while two sausages batches were contaminated with the same field strain at two different concentrations, 10 CFU/g and 10 CFU/g, before storing them in proper conditions to allow for their ripening. A third sausage batch was contaminated by adding 2 g of wild boar lymph nodal tissue with active tuberculous lesions to the meat mixture.
View Article and Find Full Text PDFHepatitis E virus (HEV) infection is an emerging public health problem in industrialized countries. The infection is associated with waterborne epidemics and transmitted via faecal-oral route. Zoonotic cases of HEV in humans have increased in Europe, and HEV genotype 3 (HEV-3) is the most frequent among humans and animals.
View Article and Find Full Text PDFChanges in surface energy and electrical conductivity of polyimide (PI)-based nanocomposite films filled with carbon nanotubes (CNTs) induced by UV exposure are gaining considerable interest in microelectronic, aeronautical, and aerospace applications. However, the underlying mechanism of PI photochemistry and oxidation reactions induced by UV irradiation upon the surface in the presence of CNTs is still not clear. Here, we probed the interplay between CNTs and PIs under UV exposure in the surface properties of CNT/PI nanocomposite films.
View Article and Find Full Text PDFRespiratory failure is the leading cause of death in patients with severe SARS-CoV-2 infection, but the host response at the lung tissue level is poorly understood. Here we performed single-nucleus RNA sequencing of about 116,000 nuclei from the lungs of nineteen individuals who died of COVID-19 and underwent rapid autopsy and seven control individuals. Integrated analyses identified substantial alterations in cellular composition, transcriptional cell states, and cell-to-cell interactions, thereby providing insight into the biology of lethal COVID-19.
View Article and Find Full Text PDFAmong the new contaminants relevant for environment, one of the most significant roles is played by pharmaceuticals like antibiotic products for either human or veterinary use. Their presence could cause serious damage to bacteria and microfauna, like nematodes. Within the widely investigated nematodes, very little is known about the interaction between antibiotics and entomopathogenic nematodes (EPN).
View Article and Find Full Text PDFThe efficacy of combining radiation therapy with immune checkpoint inhibitor blockade to treat brain tumors is currently the subject of multiple investigations and holds significant therapeutic promise. However, the long-term effects of this combination therapy on the normal brain tissue are unknown. Here, we examined mice that were intracranially implanted with murine glioma cell line and became long-term survivors after treatment with a combination of 10 Gy cranial irradiation (RT) and anti-PD-1 checkpoint blockade (aPD-1).
View Article and Find Full Text PDFAn investigation was carried out to detect the presence of Mycobacterium bovis in slaughterhouses where intradermal tuberculin test positive cattle were slaughtered, and to evaluate the risk of contamination by M. bovis among exposed slaughterhouse workers. Swabs were taken from the carcasses of slaughtered animals showing autoptic signs of non-generalized forms of tuberculosis, thus authorized for free consumption.
View Article and Find Full Text PDFAim: The study aimed at evaluating the concentration levels of organochlorine pollutants in donkey milk and their modulation on the intestinal strongyle infection. Risk evaluation for consumer health was also investigated.
Methods: We analyzed milk of grazing donkeys living in areas of Southern of Italy affected by organochlorine compounds environmental pollution and parasite infection.
Neonatal hypoxic-ischemic encephalopathy remains the most important neurological problem of the newborn. Delays in diagnosing perinatal brain injuries are common, preventing access to acute therapies. Therefore, there is a critical need for therapeutic strategies that are beneficial when delivered beyond 24 h after birth.
View Article and Find Full Text PDFIntroduction: Glioblastoma multiforme (GBM) is a deadly brain tumor with a short expected median survival, despite current standard-of-care treatment. We explored the combination of intermediate stereotactic dose radiation therapy and immune checkpoint inhibitor therapy as a novel treatment strategy for GBM.
Methods: Glioma xenograft-bearing mice were exposed to high dose brain-directed radiation (10 Gy single exposure) as well as mouse anti-PD-1 antibody.
General hygienic parameters and selected foodborne pathogens in raw milk cheeses at the retail level were evaluated. A total of 245 raw milk cheese samples were analysed for total bacterial count, , , spp., , , and staphylococcal enterotoxin.
View Article and Find Full Text PDFThe most important Italian population of the Eurasian otter (Lutra lutra) occurs in the southern part of the peninsula with two isolated sub-populations of about 250 adult individuals. The Eurasian otter is considered to be near threatened and it is a fully protected species. The aims of this study were to investigate for the first time the occurrence and characterize the parvoviruses included in the species Carnivore protoparvovirus 1 in seven carcasses of road-killed Eurasian otters from the southern Italy.
View Article and Find Full Text PDFA new species of the genus Paractinolaimus, namely, Paractinolaimus persicus sp. n., is described.
View Article and Find Full Text PDFStudy Design: Experimental study.
Objectives: To evaluate the efficacy of Angiotensin-converting enzyme inhibitor Ramipril, as a mitigator of radiation-induced spinal cord injury.
Setting: Stony Brook University, Stony Brook, NY, USA.
Purpose: This study evaluates FTY720/Fingolimod, modulator of sphingosine-1-phosphate (S1P) receptor, as a potential mitigator of radiation-induced neurocognitive dysfunction.
Methods And Materials: To study radiation-induced neurocognitive deficits, 6 week-old C57/Bl/6J mice received 0 or 7Gy cranial irradiation and were treated with FTY720 or vehicle for seven weeks. Fear conditioning and Morris water maze were then employed to test learning and memory.
Aim: The study aims at investigating whether, and if so, to what extent the strong presence of urban and industrial waste in a territory may cause PCB contamination in goat milk produced therein.
Methods: We compared PCB concentrations in goat milk from three different locations in the Campania region (Italy). One of the three locations, together with its surrounding area, has long suffered from illegal waste disposal and burning mainly by the so-called Ecomafia.
Many insects are reported to damage cultivated chestnut (Castanea sativa Mill.; Fagaceae) in Italy, but the most important pests of chestnut fruits are weevils (Curculio elephas Gyll. and Curculio glandium Marsh.
View Article and Find Full Text PDFDuring a 5-year period from 2010 to 2014, n = 919 samples of feed and raw materials were analyzed for aflatoxin B (AFB) contamination using accredited ELISA screening methods. Only 0.76 % of these samples were non-compliant with maximum levels set by the European Union Regulation 32/2002.
View Article and Find Full Text PDFThe occurrence of harmful cyanobacterial blooms in surface waters is often accompanied by the production of a variety of cyanotoxins, and these toxins are designed to target in humans specific organs on which they act. When introduced into the soil ecosystem by spray irrigation of crops, they may affect the same molecular pathways in plants having identical or similar target organs, tissues, cells, or biomolecules. There are also several indications that terrestrial plants, including crops, can bioaccumulate cyanotoxins and present, therefore, potential health hazards for humans.
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