Publications by authors named "Claus Asger Lykkebo"
Article Synopsis
- Perfluorooctane sulfonic acid (PFOS) is a long-lasting chemical commonly found in various everyday products and is primarily ingested through food.
- A study in rats compared the effects of high-fiber (HF) versus low-fiber (LF) diets on PFOS absorption and removal from the body, finding that HF reduced PFOS levels in the bloodstream while increasing its excretion in feces.
- The findings indicate that a diet rich in soluble dietary fibers may enhance the elimination of PFOS and alter gut microbiota composition.
Perfluorooctane sulfonic acid (PFOS) is a manmade legacy compound belonging to the group of persistent per- and polyfluorinated substances (PFAS). While many adverse health effects of PFOS have been identified, knowledge about its effect on the intestinal microbiota is scarce. The microbial community inhabiting the gut of mammals plays an important role in health, for instance by affecting the uptake, excretion, and bioavailability of some xenobiotic toxicants.
View Article and Find Full Text PDFPerfluorooctanesulfonic acid (PFOS) is a persistent anthropogenic chemical that can affect the thyroid hormone system in humans and animals. In adults, thyroid hormones (THs) are regulated by the hypothalamic-pituitary-thyroid (HPT) axis, but also by organs such as the liver and potentially the gut microbiota. PFOS and other xenobiotics can therefore disrupt the TH system at various locations and through different mechanisms.
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