Publications by authors named "Claudio Vergara"

Article Synopsis
  • The study investigates the effectiveness of different virus transport media (VTM) for transporting nasopharyngeal swab samples during the COVID-19 pandemic in Santiago, Chile.
  • Five VTM types were compared: DNA/RNA Shield™, NAT, VTM-N, Ezmedlab™, and phosphate-buffered saline (PBS), using RT-qPCR amplification profiles.
  • Results indicated that DNA/RNA Shield™ performed best, showing higher fluorescence and lower Cq values, while PBS performed poorly and may hinder accurate sample diagnosis.
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Interleukin (IL)-4 and IL-13 play a central role in T helper 2 immune response in mammals. The cell signalling is mediated by the type I heterodimeric receptor containing the IL-4Rα and γC chains, and the type II receptors formed by IL-4Rα and IL-13Rα1. In salmonid species, three paralogues of the IL-4 and IL-13 cytokines have been reported, il-4/13a, il-4/13b1 and il-4/13b2.

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Valdecoxib addition quenches the intrinsic human serum albumin (HSA) fluorescence. This allows an evaluation of the drug-protein association. However, both the number of binding sites and their affinity for the drug depend upon the methodology employed for their evaluation and the employed protein concentration.

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