Advances in the medical treatment and diagnosis of intracranial hemorrhage associated with oral anticoagulation.

Introduction: With the increasing prevalence of atrial fibrillation (AF), it entails expanding oral anticoagulants (OACs) use, carrying a higher risk of associated hemorrhagic events, including intracranial hemorrhage (ICH). Despite advances in OACs development with a better safety profile and reversal agent for these anticoagulants, there is still no consensus on the optimal management of patients with OACs-associated ICH.

Areas Covered: In this review, the authors have carried out an exhaustive search on the advances in recent years.

Long-term survival of glioblastoma: A systematic analysis of literature about a case.

Introduction: In spite of the changes for the treatment of glioblastoma since 2005, we have not seen differences between long-survival patients of more than 10 years showing a value minor than 1%.

Material And Method: We realize a systematic analysis and identify important factors for long survivor patients. We also show an own case with more of 20 years of survival.