Publications by authors named "Claudio Marino"

To the Editor, Erectile dysfunction (ED) is one of the most prevalent conditions affecting men globally, with significant psychological and social consequences. The prevalence varies across different populations, and it is estimated around 50% in men aged between 40 to 70. The etiology of ED is multifactorial, involving a complex crosstalk between psychological, hormonal, neurogenic, vascular, and structural factors [.

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Article Synopsis
  • Peyronie's disease (PD) affects around 10% of men globally and involves a complication in penile connective tissue, with increased interest in nonsurgical treatments like hyaluronic acid (HA) injections.
  • A study conducted from January 2020 to March 2023 involved 62 patients with stable-phase PD who received three HA injections, combined with vacuum therapy and exercises, to assess curvatures and patient-reported outcomes.
  • Results showed significant improvements in penile curvature (from 52.7° to 40.3°) and psychological well-being, with 80.6% of patients reporting subjective improvements after treatment, while only 12.9% saw no changes.
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Background: Penile injection of foreign materials is an obsolete practice often performed by non-medical personnel in order to enlarge penile size.

Methods: A systematic review of the literature from 1956 to 2022 was conducted in accordance with the general guidelines recommended by the Primary Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement. We included full papers published from 1956 to 2022.

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Article Synopsis
  • The study aimed to identify predictors for cribriform variant status and perineural invasion (PNI) in patients undergoing robot-assisted radical prostatectomy (RARP), focusing on upgrading rates between biopsy and final histology.
  • Among the 265 prostate cancer patients analyzed, 55.8% displayed cribriform variant and 71.1% exhibited PNI, with total tumor length and PIRADS scores identified as significant predictors.
  • In low- and intermediate-risk patients, upgrading rates were notably high (74.4% and 78.0% respectively), highlighting the importance of PIRADS scores in guiding treatment decisions.
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Massive scrotal elephantiasis is a rare disease that usually requires a surgical approach. Lymphedema of the genitalia can have a different presentation that requires different treatment. The present study describes the case of a 43-year-old Caucasian male patient by scrotal elephantiasis of unknown causes with a buried penis.

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