Publications by authors named "Claudio Mangia"
Article Synopsis
- Coronary failure is the leading cause of death globally, and the study aims to evaluate the biomarkers interleukin 18 (IL-18) and thrombus precursor protein (TpP) for early assessment of coronary artery disease (CAD).
- The research involved 119 patients divided into three groups: those with acute coronary syndrome, chronic CAD, and a control group without coronary lesions but at risk for CAD, with statistical analyses conducted to compare biomarker levels.
- Results showed significantly higher levels of IL-18 and TpP in the acute coronary syndrome group compared to the others, indicating these biomarkers may be linked to atherosclerotic plaque instability in acute phases of CAD, but not in chronic cases.
Background: The increasing use of conducted electronic weapons (CEW) cause concern regarding its secure application, specially regarding the implications in the cardiovascular system.
Methods: The objective was to determine Spark CEW safety through cardiovascular parameters analysis of healthy volunteers subjected to its use.
Results: Volunteers over 18years without cardiovascular disease or recent use of illegal drugs were submitted, before and after being affected with Spark CEW, to clinical evaluation; blood collection for serum laboratory tests; transthoracic electrocardiography at rest, transthoracic echodopplercardiogram and 24hour Holter.